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Nanobodies effectively modulate the enzymatic activity of CD38 and allow specific imaging of CD38+ tumors in mouse models in vivo.
Fumey W, Koenigsdorf J, Kunick V, Menzel S, Schütze K, Unger M, Schriewer L, Haag F, Adam G, Oberle A, Binder M, Fliegert R, Guse A, Zhao YJ, Cheung Lee H, Malavasi F, Goldbaum F, van Hegelsom R, Stortelers C, Bannas P, Koch-Nolte F. Fumey W, et al. Sci Rep. 2017 Oct 30;7(1):14289. doi: 10.1038/s41598-017-14112-6. Sci Rep. 2017. PMID: 29084989 Free PMC article.
P2X7-mediated ATP secretion is accompanied by depletion of cytosolic ATP.
Johnsen B, Kaschubowski KE, Nader S, Schneider E, Nicola JA, Fliegert R, Wolf IMA, Guse AH, Nikolaev VO, Koch-Nolte F, Haag F. Johnsen B, et al. Purinergic Signal. 2019 Jun;15(2):155-166. doi: 10.1007/s11302-019-09654-5. Epub 2019 Apr 23. Purinergic Signal. 2019. PMID: 31016551 Free PMC article.
Flow Cytometry of Membrane Purinoreceptors.
Schwarz N, Junge M, Haag F, Koch-Nolte F. Schwarz N, et al. Methods Mol Biol. 2020;2041:117-136. doi: 10.1007/978-1-4939-9717-6_8. Methods Mol Biol. 2020. PMID: 31646484
241 results