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Combined sialic acid and histone deacetylase (HDAC) inhibitor treatment up-regulates the neuroblastoma antigen GD2.
van den Bijgaart RJE, Kroesen M, Wassink M, Brok IC, Kers-Rebel ED, Boon L, Heise T, van Scherpenzeel M, Lefeber DJ, Boltje TJ, den Brok MH, Hoogerbrugge PM, Büll C, Adema GJ. van den Bijgaart RJE, et al. Among authors: den brok mh. J Biol Chem. 2019 Mar 22;294(12):4437-4449. doi: 10.1074/jbc.RA118.002763. Epub 2019 Jan 22. J Biol Chem. 2019. PMID: 30670592 Free PMC article.
Sialic acids sweeten a tumor's life.
Büll C, Stoel MA, den Brok MH, Adema GJ. Büll C, et al. Among authors: den brok mh. Cancer Res. 2014 Jun 15;74(12):3199-204. doi: 10.1158/0008-5472.CAN-14-0728. Epub 2014 May 15. Cancer Res. 2014. PMID: 24830719 Review.
Sweet escape: sialic acids in tumor immune evasion.
Büll C, den Brok MH, Adema GJ. Büll C, et al. Among authors: den brok mh. Biochim Biophys Acta. 2014 Aug;1846(1):238-46. doi: 10.1016/j.bbcan.2014.07.005. Epub 2014 Jul 12. Biochim Biophys Acta. 2014. PMID: 25026312 Review.
Intra-adrenal murine TH-MYCN neuroblastoma tumors grow more aggressive and exhibit a distinct tumor microenvironment relative to their subcutaneous equivalents.
Kroesen M, Brok IC, Reijnen D, van Hout-Kuijer MA, Zeelenberg IS, Den Brok MH, Hoogerbrugge PM, Adema GJ. Kroesen M, et al. Among authors: brok ic, den brok mh. Cancer Immunol Immunother. 2015 May;64(5):563-72. doi: 10.1007/s00262-015-1663-y. Epub 2015 Feb 17. Cancer Immunol Immunother. 2015. PMID: 25687736 Free PMC article.
Sialic Acid Glycoengineering Using an Unnatural Sialic Acid for the Detection of Sialoglycan Biosynthesis Defects and On-Cell Synthesis of Siglec Ligands.
Büll C, Heise T, Beurskens DM, Riemersma M, Ashikov A, Rutjes FP, van Kuppevelt TH, Lefeber DJ, den Brok MH, Adema GJ, Boltje TJ. Büll C, et al. Among authors: den brok mh. ACS Chem Biol. 2015 Oct 16;10(10):2353-63. doi: 10.1021/acschembio.5b00501. Epub 2015 Aug 10. ACS Chem Biol. 2015. PMID: 26258433
40 results