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Screening of a PDE-focused library identifies imidazoles with in vitro and in vivo antischistosomal activity.
Botros SS, William S, Sabra AA, El-Lakkany NM, Seif El-Din SH, García-Rubia A, Sebastián-Pérez V, Blaazer AR, de Heuvel E, Sijm M, Zheng Y, Salado IG, Munday JC, Maes L, de Esch IJP, Sterk GJ, Augustyns K, Leurs R, Gil C, De Koning HP. Botros SS, et al. Among authors: william s. Int J Parasitol Drugs Drug Resist. 2019 Apr;9:35-43. doi: 10.1016/j.ijpddr.2019.01.001. Epub 2019 Jan 14. Int J Parasitol Drugs Drug Resist. 2019. PMID: 30669086 Free PMC article.
Antischistosomal activity of hexadecyloxypropyl cyclic 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine and other alkoxyalkyl esters of acyclic nucleoside phosphonates assessed by schistosome worm killing in vitro.
Botros SS, William S, Beadle JR, Valiaeva N, Hostetler KY. Botros SS, et al. Among authors: william s. Antimicrob Agents Chemother. 2009 Dec;53(12):5284-7. doi: 10.1128/AAC.00840-09. Epub 2009 Aug 24. Antimicrob Agents Chemother. 2009. PMID: 19704122 Free PMC article.
MCR synthesis of praziquantel derivatives.
Liu H, William S, Herdtweck E, Botros S, Dömling A. Liu H, et al. Among authors: william s. Chem Biol Drug Des. 2012 Apr;79(4):470-7. doi: 10.1111/j.1747-0285.2011.01288.x. Epub 2012 Jan 30. Chem Biol Drug Des. 2012. PMID: 22151001 Free PMC article.
73 results