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Combinatorial glucose, nicotinic acid and N-acetylcysteine therapy has synergistic effect in preclinical C. elegans and zebrafish models of mitochondrial complex I disease.
Guha S, Mathew ND, Konkwo C, Ostrovsky J, Kwon YJ, Polyak E, Seiler C, Bennett M, Xiao R, Zhang Z, Nakamaru-Ogiso E, Falk MJ. Guha S, et al. Among authors: mathew nd. Hum Mol Genet. 2021 May 12;30(7):536-551. doi: 10.1093/hmg/ddab059. Hum Mol Genet. 2021. PMID: 33640978 Free PMC article.
The FusX TALE Base Editor (FusXTBE) for Rapid Mitochondrial DNA Programming of Human Cells In Vitro and Zebrafish Disease Models In Vivo.
Sabharwal A, Kar B, Restrepo-Castillo S, Holmberg SR, Mathew ND, Kendall BL, Cotter RP, WareJoncas Z, Seiler C, Nakamaru-Ogiso E, Clark KJ, Ekker SC. Sabharwal A, et al. Among authors: mathew nd. CRISPR J. 2021 Dec;4(6):799-821. doi: 10.1089/crispr.2021.0061. Epub 2021 Nov 30. CRISPR J. 2021. PMID: 34847747 Free PMC article.
Using C. elegans Forward and Reverse Genetics to Identify New Compounds with Anthelmintic Activity.
Mathew MD, Mathew ND, Miller A, Simpson M, Au V, Garland S, Gestin M, Edgley ML, Flibotte S, Balgi A, Chiang J, Giaever G, Dean P, Tung A, Roberge M, Roskelley C, Forge T, Nislow C, Moerman D. Mathew MD, et al. Among authors: mathew nd. PLoS Negl Trop Dis. 2016 Oct 18;10(10):e0005058. doi: 10.1371/journal.pntd.0005058. eCollection 2016 Oct. PLoS Negl Trop Dis. 2016. PMID: 27755544 Free PMC article.
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