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Page 1
KLF9-dependent ROS regulate melanoma progression in stage-specific manner.
Bagati A, Moparthy S, Fink EE, Bianchi-Smiraglia A, Yun DH, Kolesnikova M, Udartseva OO, Wolff DW, Roll MV, Lipchick BC, Han Z, Kozlova NI, Jowdy P, Berman AE, Box NF, Rodriguez C, Bshara W, Kandel ES, Soengas MS, Paragh G, Nikiforov MA. Bagati A, et al. Among authors: moparthy s. Oncogene. 2019 May;38(19):3585-3597. doi: 10.1038/s41388-019-0689-6. Epub 2019 Jan 21. Oncogene. 2019. PMID: 30664687 Free PMC article.
FOXQ1 controls the induced differentiation of melanocytic cells.
Bagati A, Bianchi-Smiraglia A, Moparthy S, Kolesnikova K, Fink EE, Kolesnikova M, Roll MV, Jowdy P, Wolff DW, Polechetti A, Yun DH, Lipchick BC, Paul LM, Wrazen B, Moparthy K, Mudambi S, Morozevich GE, Georgieva SG, Wang J, Shafirstein G, Liu S, Kandel ES, Berman AE, Box NF, Paragh G, Nikiforov MA. Bagati A, et al. Among authors: moparthy s. Cell Death Differ. 2018 Jun;25(6):1040-1049. doi: 10.1038/s41418-018-0066-y. Epub 2018 Feb 20. Cell Death Differ. 2018. PMID: 29463842 Free PMC article.
Microphthalmia-associated transcription factor suppresses invasion by reducing intracellular GTP pools.
Bianchi-Smiraglia A, Bagati A, Fink EE, Moparthy S, Wawrzyniak JA, Marvin EK, Battaglia S, Jowdy P, Kolesnikova M, Foley CE, Berman AE, Kozlova NI, Lipchick BC, Paul-Rosner LM, Bshara W, Ackroyd JJ, Shewach DS, Nikiforov MA. Bianchi-Smiraglia A, et al. Among authors: moparthy s. Oncogene. 2017 Jan 5;36(1):84-96. doi: 10.1038/onc.2016.178. Epub 2016 May 16. Oncogene. 2017. PMID: 27181209 Free PMC article.
Melanoma Suppressor Functions of the Carcinoma Oncogene FOXQ1.
Bagati A, Bianchi-Smiraglia A, Moparthy S, Kolesnikova K, Fink EE, Lipchick BC, Kolesnikova M, Jowdy P, Polechetti A, Mahpour A, Ross J, Wawrzyniak JA, Yun DH, Paragh G, Kozlova NI, Berman AE, Wang J, Liu S, Nemeth MJ, Nikiforov MA. Bagati A, et al. Among authors: moparthy s. Cell Rep. 2017 Sep 19;20(12):2820-2832. doi: 10.1016/j.celrep.2017.08.057. Cell Rep. 2017. PMID: 28930679 Free PMC article.
Inhibition of the aryl hydrocarbon receptor/polyamine biosynthesis axis suppresses multiple myeloma.
Bianchi-Smiraglia A, Bagati A, Fink EE, Affronti HC, Lipchick BC, Moparthy S, Long MD, Rosario SR, Lightman SM, Moparthy K, Wolff DW, Yun DH, Han Z, Polechetti A, Roll MV, Gitlin II, Leonova KI, Rowsam AM, Kandel ES, Gudkov AV, Bergsagel PL, Lee KP, Smiraglia DJ, Nikiforov MA. Bianchi-Smiraglia A, et al. Among authors: moparthy s. J Clin Invest. 2018 Oct 1;128(10):4682-4696. doi: 10.1172/JCI70712. Epub 2018 Sep 10. J Clin Invest. 2018. PMID: 30198908 Free PMC article.
The fatty acid elongase ELOVL6 regulates bortezomib resistance in multiple myeloma.
Lipchick BC, Utley A, Han Z, Moparthy S, Yun DH, Bianchi-Smiraglia A, Wolff DW, Fink E, Liu L, Furdui CM, Lee J, Lee KP, Nikiforov MA. Lipchick BC, et al. Among authors: moparthy s. Blood Adv. 2021 Apr 13;5(7):1933-1946. doi: 10.1182/bloodadvances.2020002578. Blood Adv. 2021. PMID: 33821992 Free PMC article.
Phosphorylation of guanosine monophosphate reductase triggers a GTP-dependent switch from pro- to anti-oncogenic function of EPHA4.
Wolff DW, Deng Z, Bianchi-Smiraglia A, Foley CE, Han Z, Wang X, Shen S, Rosenberg MM, Moparthy S, Yun DH, Chen J, Baker BK, Roll MV, Magiera AJ, Li J, Hurley E, Feltri ML, Cox AO, Lee J, Furdui CM, Liu L, Bshara W, LaConte LEW, Kandel ES, Pasquale EB, Qu J, Hedstrom L, Nikiforov MA. Wolff DW, et al. Among authors: moparthy s. Cell Chem Biol. 2022 Jun 16;29(6):970-984.e6. doi: 10.1016/j.chembiol.2022.01.007. Epub 2022 Feb 10. Cell Chem Biol. 2022. PMID: 35148834 Free PMC article.
Pharmacological targeting of guanosine monophosphate synthase suppresses melanoma cell invasion and tumorigenicity.
Bianchi-Smiraglia A, Wawrzyniak JA, Bagati A, Marvin EK, Ackroyd J, Moparthy S, Bshara W, Fink EE, Foley CE, Morozevich GE, Berman AE, Shewach DS, Nikiforov MA. Bianchi-Smiraglia A, et al. Among authors: moparthy s. Cell Death Differ. 2015 Nov;22(11):1858-64. doi: 10.1038/cdd.2015.47. Epub 2015 Apr 24. Cell Death Differ. 2015. PMID: 25909885 Free PMC article.
Internally ratiometric fluorescent sensors for evaluation of intracellular GTP levels and distribution.
Bianchi-Smiraglia A, Rana MS, Foley CE, Paul LM, Lipchick BC, Moparthy S, Moparthy K, Fink EE, Bagati A, Hurley E, Affronti HC, Bakin AV, Kandel ES, Smiraglia DJ, Feltri ML, Sousa R, Nikiforov MA. Bianchi-Smiraglia A, et al. Among authors: moparthy s. Nat Methods. 2017 Oct;14(10):1003-1009. doi: 10.1038/nmeth.4404. Epub 2017 Sep 4. Nat Methods. 2017. PMID: 28869758 Free PMC article.
12 results