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KLF9-dependent ROS regulate melanoma progression in stage-specific manner.
Bagati A, Moparthy S, Fink EE, Bianchi-Smiraglia A, Yun DH, Kolesnikova M, Udartseva OO, Wolff DW, Roll MV, Lipchick BC, Han Z, Kozlova NI, Jowdy P, Berman AE, Box NF, Rodriguez C, Bshara W, Kandel ES, Soengas MS, Paragh G, Nikiforov MA. Bagati A, et al. Oncogene. 2019 May;38(19):3585-3597. doi: 10.1038/s41388-019-0689-6. Epub 2019 Jan 21. Oncogene. 2019. PMID: 30664687 Free PMC article.
Microphthalmia-associated transcription factor suppresses invasion by reducing intracellular GTP pools.
Bianchi-Smiraglia A, Bagati A, Fink EE, Moparthy S, Wawrzyniak JA, Marvin EK, Battaglia S, Jowdy P, Kolesnikova M, Foley CE, Berman AE, Kozlova NI, Lipchick BC, Paul-Rosner LM, Bshara W, Ackroyd JJ, Shewach DS, Nikiforov MA. Bianchi-Smiraglia A, et al. Among authors: bagati a. Oncogene. 2017 Jan 5;36(1):84-96. doi: 10.1038/onc.2016.178. Epub 2016 May 16. Oncogene. 2017. PMID: 27181209 Free PMC article.
FOXQ1 controls the induced differentiation of melanocytic cells.
Bagati A, Bianchi-Smiraglia A, Moparthy S, Kolesnikova K, Fink EE, Kolesnikova M, Roll MV, Jowdy P, Wolff DW, Polechetti A, Yun DH, Lipchick BC, Paul LM, Wrazen B, Moparthy K, Mudambi S, Morozevich GE, Georgieva SG, Wang J, Shafirstein G, Liu S, Kandel ES, Berman AE, Box NF, Paragh G, Nikiforov MA. Bagati A, et al. Cell Death Differ. 2018 Jun;25(6):1040-1049. doi: 10.1038/s41418-018-0066-y. Epub 2018 Feb 20. Cell Death Differ. 2018. PMID: 29463842 Free PMC article.
Pharmacological targeting of guanosine monophosphate synthase suppresses melanoma cell invasion and tumorigenicity.
Bianchi-Smiraglia A, Wawrzyniak JA, Bagati A, Marvin EK, Ackroyd J, Moparthy S, Bshara W, Fink EE, Foley CE, Morozevich GE, Berman AE, Shewach DS, Nikiforov MA. Bianchi-Smiraglia A, et al. Among authors: bagati a. Cell Death Differ. 2015 Nov;22(11):1858-64. doi: 10.1038/cdd.2015.47. Epub 2015 Apr 24. Cell Death Differ. 2015. PMID: 25909885 Free PMC article.
Nrf2 amplifies oxidative stress via induction of Klf9.
Zucker SN, Fink EE, Bagati A, Mannava S, Bianchi-Smiraglia A, Bogner PN, Wawrzyniak JA, Foley C, Leonova KI, Grimm MJ, Moparthy K, Ionov Y, Wang J, Liu S, Sexton S, Kandel ES, Bakin AV, Zhang Y, Kaminski N, Segal BH, Nikiforov MA. Zucker SN, et al. Among authors: bagati a. Mol Cell. 2014 Mar 20;53(6):916-928. doi: 10.1016/j.molcel.2014.01.033. Epub 2014 Mar 6. Mol Cell. 2014. PMID: 24613345 Free PMC article.
Melanoma Suppressor Functions of the Carcinoma Oncogene FOXQ1.
Bagati A, Bianchi-Smiraglia A, Moparthy S, Kolesnikova K, Fink EE, Lipchick BC, Kolesnikova M, Jowdy P, Polechetti A, Mahpour A, Ross J, Wawrzyniak JA, Yun DH, Paragh G, Kozlova NI, Berman AE, Wang J, Liu S, Nemeth MJ, Nikiforov MA. Bagati A, et al. Cell Rep. 2017 Sep 19;20(12):2820-2832. doi: 10.1016/j.celrep.2017.08.057. Cell Rep. 2017. PMID: 28930679 Free PMC article.
Inhibition of the aryl hydrocarbon receptor/polyamine biosynthesis axis suppresses multiple myeloma.
Bianchi-Smiraglia A, Bagati A, Fink EE, Affronti HC, Lipchick BC, Moparthy S, Long MD, Rosario SR, Lightman SM, Moparthy K, Wolff DW, Yun DH, Han Z, Polechetti A, Roll MV, Gitlin II, Leonova KI, Rowsam AM, Kandel ES, Gudkov AV, Bergsagel PL, Lee KP, Smiraglia DJ, Nikiforov MA. Bianchi-Smiraglia A, et al. Among authors: bagati a. J Clin Invest. 2018 Oct 1;128(10):4682-4696. doi: 10.1172/JCI70712. Epub 2018 Sep 10. J Clin Invest. 2018. PMID: 30198908 Free PMC article.
A purine nucleotide biosynthesis enzyme guanosine monophosphate reductase is a suppressor of melanoma invasion.
Wawrzyniak JA, Bianchi-Smiraglia A, Bshara W, Mannava S, Ackroyd J, Bagati A, Omilian AR, Im M, Fedtsova N, Miecznikowski JC, Moparthy KC, Zucker SN, Zhu Q, Kozlova NI, Berman AE, Hoek KS, Gudkov AV, Shewach DS, Morrison CD, Nikiforov MA. Wawrzyniak JA, et al. Among authors: bagati a. Cell Rep. 2013 Oct 31;5(2):493-507. doi: 10.1016/j.celrep.2013.09.015. Epub 2013 Oct 17. Cell Rep. 2013. PMID: 24139804 Free PMC article.
27 results