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Global Proteomic and Methylome Analysis in Human Induced Pluripotent Stem Cells Reveals Overexpression of a Human TLR3 Affecting Proper Innate Immune Response Signaling.
Requena J, Alvarez-Palomo AB, Codina-Pascual M, Delgado-Morales R, Moran S, Esteller M, Sal M, Juan M, Boronat Barado A, Consiglio A, Bogle OA, Wolvetang E, Ovchinnikov D, Alvarez I, Jaraquemada D, Mezquita-Pla J, Oliva R, Edel MJ. Requena J, et al. Among authors: delgado morales r. Stem Cells. 2019 Apr;37(4):476-488. doi: 10.1002/stem.2966. Epub 2019 Feb 14. Stem Cells. 2019. PMID: 30664289 Free PMC article.
A synthetic mRNA cell reprogramming method using CYCLIN D1 promotes DNA repair, generating improved genetically stable human induced pluripotent stem cells.
Alvarez-Palomo AB, Requena-Osete J, Delgado-Morales R, Moreno-Manzano V, Grau-Bove C, Tejera AM, Otero MJ, Barrot C, Santos-Barriopedro I, Vaquero A, Mezquita-Pla J, Moran S, Naya CH, Garcia-Martínez I, Pérez FV, Blasco MA, Esteller M, Edel MJ. Alvarez-Palomo AB, et al. Among authors: delgado morales r. Stem Cells. 2021 Jul;39(7):866-881. doi: 10.1002/stem.3358. Epub 2021 Mar 3. Stem Cells. 2021. PMID: 33621399
Opening up the DNA methylome of dementia.
Delgado-Morales R, Esteller M. Delgado-Morales R, et al. Mol Psychiatry. 2017 Apr;22(4):485-496. doi: 10.1038/mp.2016.242. Epub 2017 Jan 3. Mol Psychiatry. 2017. PMID: 28044062 Free PMC article. Review.
Stem Cell Technology for (Epi)genetic Brain Disorders.
Riemens RJM, Soares ES, Esteller M, Delgado-Morales R. Riemens RJM, et al. Among authors: delgado morales r. Adv Exp Med Biol. 2017;978:443-475. doi: 10.1007/978-3-319-53889-1_23. Adv Exp Med Biol. 2017. PMID: 28523560 Review.
Directing neuronal cell fate in vitro: Achievements and challenges.
Riemens RJM, van den Hove DLA, Esteller M, Delgado-Morales R. Riemens RJM, et al. Among authors: delgado morales r. Prog Neurobiol. 2018 Sep;168:42-68. doi: 10.1016/j.pneurobio.2018.04.003. Epub 2018 Apr 10. Prog Neurobiol. 2018. PMID: 29653249 Free article. Review.
Inhibition of Gsk3b Reduces Nfkb1 Signaling and Rescues Synaptic Activity to Improve the Rett Syndrome Phenotype in Mecp2-Knockout Mice.
Jorge-Torres OC, Szczesna K, Roa L, Casal C, Gonzalez-Somermeyer L, Soler M, Velasco CD, Martínez-San Segundo P, Petazzi P, Sáez MA, Delgado-Morales R, Fourcade S, Pujol A, Huertas D, Llobet A, Guil S, Esteller M. Jorge-Torres OC, et al. Among authors: delgado morales r. Cell Rep. 2018 May 8;23(6):1665-1677. doi: 10.1016/j.celrep.2018.04.010. Cell Rep. 2018. PMID: 29742424 Free article.
Human DNA methylomes of neurodegenerative diseases show common epigenomic patterns.
Sanchez-Mut JV, Heyn H, Vidal E, Moran S, Sayols S, Delgado-Morales R, Schultz MD, Ansoleaga B, Garcia-Esparcia P, Pons-Espinal M, de Lagran MM, Dopazo J, Rabano A, Avila J, Dierssen M, Lott I, Ferrer I, Ecker JR, Esteller M. Sanchez-Mut JV, et al. Transl Psychiatry. 2016 Jan 19;6(1):e718. doi: 10.1038/tp.2015.214. Transl Psychiatry. 2016. PMID: 26784972 Free PMC article.
Mutations in JMJD1C are involved in Rett syndrome and intellectual disability.
Sáez MA, Fernández-Rodríguez J, Moutinho C, Sanchez-Mut JV, Gomez A, Vidal E, Petazzi P, Szczesna K, Lopez-Serra P, Lucariello M, Lorden P, Delgado-Morales R, de la Caridad OJ, Huertas D, Gelpí JL, Orozco M, López-Doriga A, Milà M, Perez-Jurado LA, Pineda M, Armstrong J, Lázaro C, Esteller M. Sáez MA, et al. Genet Med. 2016 Apr;18(4):378-85. doi: 10.1038/gim.2015.100. Epub 2015 Jul 16. Genet Med. 2016. PMID: 26181491 Free PMC article.
23 results