Stone JA - Search Results

1

Clinical and translational pharmacology of the cathepsin K inhibitor odanacatib studied for osteoporosis.

Stone JA, McCrea JB, Witter R, Zajic S, Stoch SA. Stone JA, et al. Br J Clin Pharmacol. 2019 Jun;85(6):1072-1083. doi: 10.1111/bcp.13869. Epub 2019 Mar 18. Br J Clin Pharmacol. 2019. PMID: 30663085 Free PMC article. Review.

2

Single- and multiple-dose administration of caspofungin in patients with hepatic insufficiency: implications for safety and dosing recommendations.

Mistry GC, Migoya E, Deutsch PJ, Winchell G, Hesney M, Li S, Bi S, Dilzer S, Lasseter KC, Stone JA. Mistry GC, et al. Among authors: stone ja. J Clin Pharmacol. 2007 Aug;47(8):951-61. doi: 10.1177/0091270007303764. J Clin Pharmacol. 2007. PMID: 17660480 Clinical Trial.

3

Safety, tolerability, and pharmacokinetics of raltegravir after single and multiple doses in healthy subjects.

Iwamoto M, Wenning LA, Petry AS, Laethem M, De Smet M, Kost JT, Merschman SA, Strohmaier KM, Ramael S, Lasseter KC, Stone JA, Gottesdiener KM, Wagner JA. Iwamoto M, et al. Among authors: stone ja. Clin Pharmacol Ther. 2008 Feb;83(2):293-9. doi: 10.1038/sj.clpt.6100281. Epub 2007 Aug 22. Clin Pharmacol Ther. 2008. PMID: 17713476 Clinical Trial.

4

Lack of a pharmacokinetic effect of raltegravir on midazolam: in vitro/in vivo correlation.

Iwamoto M, Kassahun K, Troyer MD, Hanley WD, Lu P, Rhoton A, Petry AS, Ghosh K, Mangin E, DeNoia EP, Wenning LA, Stone JA, Gottesdiener KM, Wagner JA. Iwamoto M, et al. Among authors: stone ja. J Clin Pharmacol. 2008 Feb;48(2):209-14. doi: 10.1177/0091270007310382. Epub 2007 Dec 12. J Clin Pharmacol. 2008. PMID: 18077730 Clinical Trial.

5

Raltegravir thorough QT/QTc study: a single supratherapeutic dose of raltegravir does not prolong the QTcF interval.

Iwamoto M, Kost JT, Mistry GC, Wenning LA, Breidinger SA, Marbury TC, Stone JA, Gottesdiener KM, Bloomfield DM, Wagner JA. Iwamoto M, et al. Among authors: stone ja. J Clin Pharmacol. 2008 Jun;48(6):726-33. doi: 10.1177/0091270008318007. Epub 2008 Apr 25. J Clin Pharmacol. 2008. PMID: 18441333 Clinical Trial.

6

Model-based decision making in early clinical development: minimizing the impact of a blood pressure adverse event.

Stroh M, Addy C, Wu Y, Stoch SA, Pourkavoos N, Groff M, Xu Y, Wagner J, Gottesdiener K, Shadle C, Wang H, Manser K, Winchell GA, Stone JA. Stroh M, et al. Among authors: stone ja. AAPS J. 2009 Mar;11(1):99-108. doi: 10.1208/s12248-009-9083-6. Epub 2009 Feb 6. AAPS J. 2009. PMID: 19199043 Free PMC article.

7

Effect of the cathepsin K inhibitor odanacatib on bone resorption biomarkers in healthy postmenopausal women: two double-blind, randomized, placebo-controlled phase I studies.

Stoch SA, Zajic S, Stone J, Miller DL, Van Dyck K, Gutierrez MJ, De Decker M, Liu L, Liu Q, Scott BB, Panebianco D, Jin B, Duong LT, Gottesdiener K, Wagner JA. Stoch SA, et al. Among authors: stone j. Clin Pharmacol Ther. 2009 Aug;86(2):175-82. doi: 10.1038/clpt.2009.60. Epub 2009 May 6. Clin Pharmacol Ther. 2009. PMID: 19421185 Clinical Trial.

8

Effect of low-, moderate-, and high-fat meals on raltegravir pharmacokinetics.

Brainard DM, Friedman EJ, Jin B, Breidinger SA, Tillan MD, Wenning LA, Stone JA, Chodakewitz JA, Wagner JA, Iwamoto M. Brainard DM, et al. Among authors: stone ja. J Clin Pharmacol. 2011 Mar;51(3):422-7. doi: 10.1177/0091270010367652. Epub 2010 May 10. J Clin Pharmacol. 2011. PMID: 20457591 Clinical Trial. No abstract available.

9

Safety and pharmacokinetics of higher doses of caspofungin in healthy adult participants.

Migoya EM, Mistry GC, Stone JA, Comisar W, Sun P, Norcross A, Bi S, Winchell GA, Ghosh K, Uemera N, Deutsch PJ, Wagner JA. Migoya EM, et al. Among authors: stone ja. J Clin Pharmacol. 2011 Feb;51(2):202-11. doi: 10.1177/0091270010374853. Epub 2010 Aug 2. J Clin Pharmacol. 2011. PMID: 20679501 Clinical Trial.

10

Lack of a clinically meaningful pharmacokinetic effect of rifabutin on raltegravir: in vitro/in vivo correlation.

Brainard DM, Kassahun K, Wenning LA, Petry AS, Liu C, Lunceford J, Hariparsad N, Eisenhandler R, Norcross A, DeNoia EP, Stone JA, Wagner JA, Iwamoto M. Brainard DM, et al. Among authors: stone ja. J Clin Pharmacol. 2011 Jun;51(6):943-50. doi: 10.1177/0091270010375959. Epub 2010 Sep 17. J Clin Pharmacol. 2011. PMID: 20852006 Clinical Trial.

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