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Benzothiopyranoindole- and pyridothiopyranoindole-based antiproliferative agents targeting topoisomerases.
Salerno S, La Pietra V, Hyeraci M, Taliani S, Robello M, Barresi E, Milite C, Simorini F, García-Argáez AN, Marinelli L, Novellino E, Da Settimo F, Marini AM, Dalla Via L. Salerno S, et al. Among authors: garcia argaez an. Eur J Med Chem. 2019 Mar 1;165:46-58. doi: 10.1016/j.ejmech.2019.01.015. Epub 2019 Jan 9. Eur J Med Chem. 2019. PMID: 30660826
Investigation of new 2-aryl substituted Benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors targeting vascular endothelial growth factor receptor 2.
Salerno S, Marini AM, Fornaciari G, Simorini F, La Motta C, Taliani S, Sartini S, Da Settimo F, García-Argáez AN, Gia O, Cosconati S, Novellino E, D'Ocon P, Fioravanti A, Orlandi P, Bocci G, Dalla Via L. Salerno S, et al. Eur J Med Chem. 2015 Oct 20;103:29-43. doi: 10.1016/j.ejmech.2015.08.027. Epub 2015 Aug 14. Eur J Med Chem. 2015. PMID: 26318056
New insights in the structure-activity relationships of 2-phenylamino-substituted benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors.
Salerno S, García-Argáez AN, Barresi E, Taliani S, Simorini F, La Motta C, Amendola G, Tomassi S, Cosconati S, Novellino E, Da Settimo F, Marini AM, Via LD. Salerno S, et al. Among authors: garcia argaez an. Eur J Med Chem. 2018 Apr 25;150:446-456. doi: 10.1016/j.ejmech.2018.03.013. Epub 2018 Mar 7. Eur J Med Chem. 2018. PMID: 29547832
Discovery of Pyrido[3',2':5,6]thiopyrano[4,3-d]pyrimidine-Based Antiproliferative Multikinase Inhibitors.
Salerno S, Barresi E, García-Argáez AN, Taliani S, Simorini F, Amendola G, Tomassi S, Cosconati S, Novellino E, Da Settimo F, Marini AM, Dalla Via L. Salerno S, et al. Among authors: garcia argaez an. ACS Med Chem Lett. 2019 Jan 17;10(4):457-462. doi: 10.1021/acsmedchemlett.8b00499. eCollection 2019 Apr 11. ACS Med Chem Lett. 2019. PMID: 30996779 Free PMC article.
Boehmeriasin A as new lead compound for the inhibition of topoisomerases and SIRT2.
Christodoulou MS, Calogero F, Baumann M, García-Argáez AN, Pieraccini S, Sironi M, Dapiaggi F, Bucci R, Broggini G, Gazzola S, Liekens S, Silvani A, Lahtela-Kakkonen M, Martinet N, Nonell-Canals A, Santamaría-Navarro E, Baxendale IR, Dalla Via L, Passarella D. Christodoulou MS, et al. Eur J Med Chem. 2015 Mar 6;92:766-75. doi: 10.1016/j.ejmech.2015.01.038. Epub 2015 Jan 20. Eur J Med Chem. 2015. PMID: 25626146
35 results