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Invasive mouse gastric adenocarcinomas arising from Lgr5+ stem cells are dependent on crosstalk between the Hedgehog/GLI2 and mTOR pathways.
Syu LJ, Zhao X, Zhang Y, Grachtchouk M, Demitrack E, Ermilov A, Wilbert DM, Zheng X, Kaatz A, Greenson JK, Gumucio DL, Merchant JL, di Magliano MP, Samuelson LC, Dlugosz AA. Syu LJ, et al. Among authors: dlugosz aa. Oncotarget. 2016 Mar 1;7(9):10255-70. doi: 10.18632/oncotarget.7182. Oncotarget. 2016. PMID: 26859571 Free PMC article.
Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer.
Steele NG, Biffi G, Kemp SB, Zhang Y, Drouillard D, Syu L, Hao Y, Oni TE, Brosnan E, Elyada E, Doshi A, Hansma C, Espinoza C, Abbas A, The S, Irizarry-Negron V, Halbrook CJ, Franks NE, Hoffman MT, Brown K, Carpenter ES, Nwosu ZC, Johnson C, Lima F, Anderson MA, Park Y, Crawford HC, Lyssiotis CA, Frankel TL, Rao A, Bednar F, Dlugosz AA, Preall JB, Tuveson DA, Allen BL, Pasca di Magliano M. Steele NG, et al. Among authors: dlugosz aa. Clin Cancer Res. 2021 Apr 1;27(7):2023-2037. doi: 10.1158/1078-0432.CCR-20-3715. Epub 2021 Jan 25. Clin Cancer Res. 2021. PMID: 33495315 Free PMC article.
Transgenic expression of interferon-γ in mouse stomach leads to inflammation, metaplasia, and dysplasia.
Syu LJ, El-Zaatari M, Eaton KA, Liu Z, Tetarbe M, Keeley TM, Pero J, Ferris J, Wilbert D, Kaatz A, Zheng X, Qiao X, Grachtchouk M, Gumucio DL, Merchant JL, Samuelson LC, Dlugosz AA. Syu LJ, et al. Among authors: dlugosz aa. Am J Pathol. 2012 Dec;181(6):2114-25. doi: 10.1016/j.ajpath.2012.08.017. Epub 2012 Oct 1. Am J Pathol. 2012. PMID: 23036899 Free PMC article.
265 results