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Covalent labeling and mass spectrometry reveal subtle higher order structural changes for antibody therapeutics.
MAbs. 2019 Apr;11(3):463-476. doi: 10.1080/19420862.2019.1565748. Epub 2019 Feb 6.
MAbs. 2019.
PMID: 30636503
Free PMC article.
Investigating Therapeutic Protein Structure with Diethylpyrocarbonate Labeling and Mass Spectrometry.
Borotto NB, Zhou Y, Hollingsworth SR, Hale JE, Graban EM, Vaughan RC, Vachet RW.
Borotto NB, et al. Among authors: graban em.
Anal Chem. 2015 Oct 20;87(20):10627-34. doi: 10.1021/acs.analchem.5b03180. Epub 2015 Oct 1.
Anal Chem. 2015.
PMID: 26399599
Free PMC article.
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Membrane Protein Binding Interactions Studied in Live Cells via Diethylpyrocarbonate Covalent Labeling Mass Spectrometry.
Kirsch ZJ, Blake JM, Huynh U, Agrohia DK, Tremblay CY, Graban EM, Vaughan RC, Vachet RW.
Kirsch ZJ, et al. Among authors: graban em.
Anal Chem. 2023 May 9;95(18):7178-7185. doi: 10.1021/acs.analchem.2c05616. Epub 2023 Apr 27.
Anal Chem. 2023.
PMID: 37102678
Free PMC article.
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