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Page 1
Development of a Human Antibody Cocktail that Deploys Multiple Functions to Confer Pan-Ebolavirus Protection.
Wec AZ, Bornholdt ZA, He S, Herbert AS, Goodwin E, Wirchnianski AS, Gunn BM, Zhang Z, Zhu W, Liu G, Abelson DM, Moyer CL, Jangra RK, James RM, Bakken RR, Bohorova N, Bohorov O, Kim DH, Pauly MH, Velasco J, Bortz RH 3rd, Whaley KJ, Goldstein T, Anthony SJ, Alter G, Walker LM, Dye JM, Zeitlin L, Qiu X, Chandran K. Wec AZ, et al. Among authors: velasco j. Cell Host Microbe. 2019 Jan 9;25(1):39-48.e5. doi: 10.1016/j.chom.2018.12.004. Cell Host Microbe. 2019. PMID: 30629917 Free PMC article.
A Two-Antibody Pan-Ebolavirus Cocktail Confers Broad Therapeutic Protection in Ferrets and Nonhuman Primates.
Bornholdt ZA, Herbert AS, Mire CE, He S, Cross RW, Wec AZ, Abelson DM, Geisbert JB, James RM, Rahim MN, Zhu W, Borisevich V, Banadyga L, Gunn BM, Agans KN, Wirchnianski AS, Goodwin E, Tierney K, Shestowsky WS, Bohorov O, Bohorova N, Velasco J, Ailor E, Kim D, Pauly MH, Whaley KJ, Alter G, Walker LM, Chandran K, Zeitlin L, Qiu X, Geisbert TW, Dye JM. Bornholdt ZA, et al. Among authors: velasco j. Cell Host Microbe. 2019 Jan 9;25(1):49-58.e5. doi: 10.1016/j.chom.2018.12.005. Cell Host Microbe. 2019. PMID: 30629918 Free PMC article.
Development of an antibody cocktail for treatment of Sudan virus infection.
Herbert AS, Froude JW, Ortiz RA, Kuehne AI, Dorosky DE, Bakken RR, Zak SE, Josleyn NM, Musiychuk K, Jones RM, Green B, Streatfield SJ, Wec AZ, Bohorova N, Bohorov O, Kim DH, Pauly MH, Velasco J, Whaley KJ, Stonier SW, Bornholdt ZA, Chandran K, Zeitlin L, Sampey D, Yusibov V, Dye JM. Herbert AS, et al. Among authors: velasco j. Proc Natl Acad Sci U S A. 2020 Feb 18;117(7):3768-3778. doi: 10.1073/pnas.1914985117. Epub 2020 Feb 3. Proc Natl Acad Sci U S A. 2020. PMID: 32015126 Free PMC article.
Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp.
Qiu X, Wong G, Audet J, Bello A, Fernando L, Alimonti JB, Fausther-Bovendo H, Wei H, Aviles J, Hiatt E, Johnson A, Morton J, Swope K, Bohorov O, Bohorova N, Goodman C, Kim D, Pauly MH, Velasco J, Pettitt J, Olinger GG, Whaley K, Xu B, Strong JE, Zeitlin L, Kobinger GP. Qiu X, et al. Among authors: velasco j. Nature. 2014 Oct 2;514(7520):47-53. doi: 10.1038/nature13777. Epub 2014 Aug 29. Nature. 2014. PMID: 25171469 Free PMC article.
A tripartite cocktail of chimeric monoclonal antibodies passively protects mice against ricin, staphylococcal enterotoxin B and Clostridium perfringens epsilon toxin.
Sully EK, Whaley K, Bohorova N, Bohorov O, Goodman C, Kim D, Pauly M, Velasco J, Holtsberg FW, Stavale E, Aman MJ, Tangudu C, Uzal FA, Mantis NJ, Zeitlin L. Sully EK, et al. Among authors: velasco j. Toxicon. 2014 Dec 15;92:36-41. doi: 10.1016/j.toxicon.2014.09.006. Epub 2014 Sep 28. Toxicon. 2014. PMID: 25260254 Free PMC article.
Monoclonal antibody therapy for Junin virus infection.
Zeitlin L, Geisbert JB, Deer DJ, Fenton KA, Bohorov O, Bohorova N, Goodman C, Kim D, Hiatt A, Pauly MH, Velasco J, Whaley KJ, Altmann F, Gruber C, Steinkellner H, Honko AN, Kuehne AI, Aman MJ, Sahandi S, Enterlein S, Zhan X, Enria D, Geisbert TW. Zeitlin L, et al. Among authors: velasco j. Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):4458-63. doi: 10.1073/pnas.1600996113. Epub 2016 Apr 4. Proc Natl Acad Sci U S A. 2016. PMID: 27044104 Free PMC article.
Therapeutic treatment of Marburg and Ravn virus infection in nonhuman primates with a human monoclonal antibody.
Mire CE, Geisbert JB, Borisevich V, Fenton KA, Agans KN, Flyak AI, Deer DJ, Steinkellner H, Bohorov O, Bohorova N, Goodman C, Hiatt A, Kim DH, Pauly MH, Velasco J, Whaley KJ, Crowe JE Jr, Zeitlin L, Geisbert TW. Mire CE, et al. Among authors: velasco j. Sci Transl Med. 2017 Apr 5;9(384):eaai8711. doi: 10.1126/scitranslmed.aai8711. Sci Transl Med. 2017. PMID: 28381540 Free PMC article.
769 results