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The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders.
Ang CE, Ma Q, Wapinski OL, Fan S, Flynn RA, Lee QY, Coe B, Onoguchi M, Olmos VH, Do BT, Dukes-Rimsky L, Xu J, Tanabe K, Wang L, Elling U, Penninger JM, Zhao Y, Qu K, Eichler EE, Srivastava A, Wernig M, Chang HY. Ang CE, et al. Among authors: do bt. Elife. 2019 Jan 10;8:e41770. doi: 10.7554/eLife.41770. Elife. 2019. PMID: 30628890 Free PMC article.
7SK-BAF axis controls pervasive transcription at enhancers.
Flynn RA, Do BT, Rubin AJ, Calo E, Lee B, Kuchelmeister H, Rale M, Chu C, Kool ET, Wysocka J, Khavari PA, Chang HY. Flynn RA, et al. Among authors: do bt. Nat Struct Mol Biol. 2016 Mar;23(3):231-8. doi: 10.1038/nsmb.3176. Epub 2016 Feb 15. Nat Struct Mol Biol. 2016. PMID: 26878240 Free PMC article.
Dissecting noncoding and pathogen RNA-protein interactomes.
Flynn RA, Martin L, Spitale RC, Do BT, Sagan SM, Zarnegar B, Qu K, Khavari PA, Quake SR, Sarnow P, Chang HY. Flynn RA, et al. Among authors: do bt. RNA. 2015 Jan;21(1):135-43. doi: 10.1261/rna.047803.114. Epub 2014 Nov 19. RNA. 2015. PMID: 25411354 Free PMC article.
Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma.
Tan JL, Fogley RD, Flynn RA, Ablain J, Yang S, Saint-André V, Fan ZP, Do BT, Laga AC, Fujinaga K, Santoriello C, Greer CB, Kim YJ, Clohessy JG, Bothmer A, Pandell N, Avagyan S, Brogie JE, van Rooijen E, Hagedorn EJ, Shyh-Chang N, White RM, Price DH, Pandolfi PP, Peterlin BM, Zhou Y, Kim TH, Asara JM, Chang HY, Young RA, Zon LI. Tan JL, et al. Among authors: do bt. Mol Cell. 2016 Apr 7;62(1):34-46. doi: 10.1016/j.molcel.2016.03.013. Mol Cell. 2016. PMID: 27058786 Free PMC article.
Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress.
Oh S, Flynn RA, Floor SN, Purzner J, Martin L, Do BT, Schubert S, Vaka D, Morrissy S, Li Y, Kool M, Hovestadt V, Jones DT, Northcott PA, Risch T, Warnatz HJ, Yaspo ML, Adams CM, Leib RD, Breese M, Marra MA, Malkin D, Lichter P, Doudna JA, Pfister SM, Taylor MD, Chang HY, Cho YJ. Oh S, et al. Among authors: do bt. Oncotarget. 2016 May 10;7(19):28169-82. doi: 10.18632/oncotarget.8612. Oncotarget. 2016. PMID: 27058758 Free PMC article.
Nucleotide imbalance decouples cell growth from cell proliferation.
Diehl FF, Miettinen TP, Elbashir R, Nabel CS, Darnell AM, Do BT, Manalis SR, Lewis CA, Vander Heiden MG. Diehl FF, et al. Among authors: do bt. Nat Cell Biol. 2022 Aug;24(8):1252-1264. doi: 10.1038/s41556-022-00965-1. Epub 2022 Aug 4. Nat Cell Biol. 2022. PMID: 35927450 Free PMC article.
Cell-programmed nutrient partitioning in the tumour microenvironment.
Reinfeld BI, Madden MZ, Wolf MM, Chytil A, Bader JE, Patterson AR, Sugiura A, Cohen AS, Ali A, Do BT, Muir A, Lewis CA, Hongo RA, Young KL, Brown RE, Todd VM, Huffstater T, Abraham A, O'Neil RT, Wilson MH, Xin F, Tantawy MN, Merryman WD, Johnson RW, Williams CS, Mason EF, Mason FM, Beckermann KE, Vander Heiden MG, Manning HC, Rathmell JC, Rathmell WK. Reinfeld BI, et al. Among authors: do bt. Nature. 2021 May;593(7858):282-288. doi: 10.1038/s41586-021-03442-1. Epub 2021 Apr 7. Nature. 2021. PMID: 33828302 Free PMC article.
Increased demand for NAD+ relative to ATP drives aerobic glycolysis.
Luengo A, Li Z, Gui DY, Sullivan LB, Zagorulya M, Do BT, Ferreira R, Naamati A, Ali A, Lewis CA, Thomas CJ, Spranger S, Matheson NJ, Vander Heiden MG. Luengo A, et al. Among authors: do bt. Mol Cell. 2021 Feb 18;81(4):691-707.e6. doi: 10.1016/j.molcel.2020.12.012. Epub 2020 Dec 30. Mol Cell. 2021. PMID: 33382985 Free PMC article.
43 results