Boehm BO - Search Results

1

Preproinsulin Designer Antigens Excluded from Endoplasmic Reticulum Suppressed Diabetes Development in NOD Mice by DNA Vaccination.

Stifter K, Schuster C, Krieger J, Spyrantis A, Boehm BO, Schirmbeck R. Stifter K, et al. Among authors: boehm bo. Mol Ther Methods Clin Dev. 2018 Dec 13;12:123-133. doi: 10.1016/j.omtm.2018.12.002. eCollection 2019 Mar 15. Mol Ther Methods Clin Dev. 2018. PMID: 30623001 Free PMC article.

2

Exploring the induction of preproinsulin-specific Foxp3(+) CD4(+) Treg cells that inhibit CD8(+) T cell-mediated autoimmune diabetes by DNA vaccination.

Stifter K, Schuster C, Schlosser M, Boehm BO, Schirmbeck R. Stifter K, et al. Among authors: boehm bo. Sci Rep. 2016 Jul 11;6:29419. doi: 10.1038/srep29419. Sci Rep. 2016. PMID: 27406624 Free PMC article.

3

Processing in the endoplasmic reticulum generates an epitope on the insulin A chain that stimulates diabetogenic CD8 T cell responses.

Brosi H, Reiser M, Rajasalu T, Spyrantis A, Oswald F, Boehm BO, Schirmbeck R. Brosi H, et al. Among authors: boehm bo. J Immunol. 2009 Dec 1;183(11):7187-95. doi: 10.4049/jimmunol.0901573. Epub 2009 Nov 4. J Immunol. 2009. PMID: 19890053

4

Deficiency in B7-H1 (PD-L1)/PD-1 coinhibition triggers pancreatic beta-cell destruction by insulin-specific, murine CD8 T-cells.

Rajasalu T, Brosi H, Schuster C, Spyrantis A, Boehm BO, Chen L, Reimann J, Schirmbeck R. Rajasalu T, et al. Among authors: boehm bo. Diabetes. 2010 Aug;59(8):1966-73. doi: 10.2337/db09-1135. Epub 2010 May 18. Diabetes. 2010. PMID: 20484136 Free PMC article.

5

A dominant insulin-specific and islet-destructive T-cell response is sufficient to activate CD8 T cells directed against the fatty-acid receptor GPR40.

Spyrantis A, Krieger J, Stifter K, Boehm BO, Schirmbeck R. Spyrantis A, et al. Among authors: boehm bo. Cell Mol Immunol. 2020 Jun;17(6):659-661. doi: 10.1038/s41423-019-0309-y. Epub 2019 Oct 24. Cell Mol Immunol. 2020. PMID: 31649307 Free PMC article. No abstract available.

6

A missing PD-L1/PD-1 coinhibition regulates diabetes induction by preproinsulin-specific CD8 T-cells in an epitope-specific manner.

Schuster C, Brosi H, Stifter K, Boehm BO, Schirmbeck R. Schuster C, et al. Among authors: boehm bo. PLoS One. 2013 Aug 19;8(8):e71746. doi: 10.1371/journal.pone.0071746. eCollection 2013. PLoS One. 2013. PMID: 23977133 Free PMC article.

7

Experimental autoimmune diabetes: a new tool to study mechanisms and consequences of insulin-specific autoimmunity.

Rajasalu T, Barth C, Spyrantis A, Durinovic-Belló I, Uibo R, Schirmbeck R, Boehm BO, Karges W. Rajasalu T, et al. Among authors: boehm bo. Ann N Y Acad Sci. 2004 Dec;1037:208-15. doi: 10.1196/annals.1337.034. Ann N Y Acad Sci. 2004. PMID: 15699519

8

PAX4 preserves endoplasmic reticulum integrity preventing beta cell degeneration in a mouse model of type 1 diabetes mellitus.

Mellado-Gil JM, Jiménez-Moreno CM, Martin-Montalvo A, Alvarez-Mercado AI, Fuente-Martin E, Cobo-Vuilleumier N, Lorenzo PI, Bru-Tari E, Herrera-Gómez Ide G, López-Noriega L, Pérez-Florido J, Santoyo-López J, Spyrantis A, Meda P, Boehm BO, Quesada I, Gauthier BR. Mellado-Gil JM, et al. Among authors: boehm bo. Diabetologia. 2016 Apr;59(4):755-65. doi: 10.1007/s00125-016-3864-0. Epub 2016 Jan 26. Diabetologia. 2016. PMID: 26813254 Free PMC article.

9

The diabetogenic, insulin-specific CD8 T cell response primed in the experimental autoimmune diabetes model in RIP-B7.1 mice.

Karges W, Rajasalu T, Spyrantis A, Wieland A, Boehm B, Schirmbeck R. Karges W, et al. Eur J Immunol. 2007 Aug;37(8):2097-103. doi: 10.1002/eji.200737222. Eur J Immunol. 2007. PMID: 17615584 Free article.

10

Long-term IKK2/NF-κB signaling in pancreatic β-cells induces immune-mediated diabetes.

Salem HH, Trojanowski B, Fiedler K, Maier HJ, Schirmbeck R, Wagner M, Boehm BO, Wirth T, Baumann B. Salem HH, et al. Among authors: boehm bo. Diabetes. 2014 Mar;63(3):960-75. doi: 10.2337/db13-1037. Epub 2013 Dec 2. Diabetes. 2014. PMID: 24296718

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