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Page 1
Cardiomyocyte Progenitor Cells as a Functional Gene Delivery Vehicle for Long-Term Biological Pacing.
Végh AMD, den Haan AD, Cócera Ortega L, Verkerk AO, Sluijter JPG, Bakker D, van Amersfoorth S, van Veen TAB, Klerk M, Seppen J, de Bakker JMT, Christoffels VM, Geerts D, Goumans MJTH, Tan HL, Boink GJJ. Végh AMD, et al. Among authors: christoffels vm. Molecules. 2019 Jan 5;24(1):181. doi: 10.3390/molecules24010181. Molecules. 2019. PMID: 30621310 Free PMC article.
Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria.
Hoogaars WM, Engel A, Brons JF, Verkerk AO, de Lange FJ, Wong LY, Bakker ML, Clout DE, Wakker V, Barnett P, Ravesloot JH, Moorman AF, Verheijck EE, Christoffels VM. Hoogaars WM, et al. Among authors: christoffels vm. Genes Dev. 2007 May 1;21(9):1098-112. doi: 10.1101/gad.416007. Genes Dev. 2007. PMID: 17473172 Free PMC article.
The cardiac sodium channel displays differential distribution in the conduction system and transmural heterogeneity in the murine ventricular myocardium.
Remme CA, Verkerk AO, Hoogaars WM, Aanhaanen WT, Scicluna BP, Annink C, van den Hoff MJ, Wilde AA, van Veen TA, Veldkamp MW, de Bakker JM, Christoffels VM, Bezzina CR. Remme CA, et al. Among authors: christoffels vm. Basic Res Cardiol. 2009 Sep;104(5):511-22. doi: 10.1007/s00395-009-0012-8. Epub 2009 Mar 3. Basic Res Cardiol. 2009. PMID: 19255801 Free PMC article.
T-box transcription factor TBX3 reprogrammes mature cardiac myocytes into pacemaker-like cells.
Bakker ML, Boink GJ, Boukens BJ, Verkerk AO, van den Boogaard M, den Haan AD, Hoogaars WM, Buermans HP, de Bakker JM, Seppen J, Tan HL, Moorman AF, 't Hoen PA, Christoffels VM. Bakker ML, et al. Among authors: christoffels vm. Cardiovasc Res. 2012 Jun 1;94(3):439-49. doi: 10.1093/cvr/cvs120. Epub 2012 Mar 14. Cardiovasc Res. 2012. PMID: 22419669
Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death.
Bezzina CR, Barc J, Mizusawa Y, Remme CA, Gourraud JB, Simonet F, Verkerk AO, Schwartz PJ, Crotti L, Dagradi F, Guicheney P, Fressart V, Leenhardt A, Antzelevitch C, Bartkowiak S, Borggrefe M, Schimpf R, Schulze-Bahr E, Zumhagen S, Behr ER, Bastiaenen R, Tfelt-Hansen J, Olesen MS, Kääb S, Beckmann BM, Weeke P, Watanabe H, Endo N, Minamino T, Horie M, Ohno S, Hasegawa K, Makita N, Nogami A, Shimizu W, Aiba T, Froguel P, Balkau B, Lantieri O, Torchio M, Wiese C, Weber D, Wolswinkel R, Coronel R, Boukens BJ, Bézieau S, Charpentier E, Chatel S, Despres A, Gros F, Kyndt F, Lecointe S, Lindenbaum P, Portero V, Violleau J, Gessler M, Tan HL, Roden DM, Christoffels VM, Le Marec H, Wilde AA, Probst V, Schott JJ, Dina C, Redon R. Bezzina CR, et al. Among authors: christoffels vm. Nat Genet. 2013 Sep;45(9):1044-9. doi: 10.1038/ng.2712. Epub 2013 Jul 21. Nat Genet. 2013. PMID: 23872634 Free PMC article.
The past, present, and future of pacemaker therapies.
Boink GJ, Christoffels VM, Robinson RB, Tan HL. Boink GJ, et al. Among authors: christoffels vm. Trends Cardiovasc Med. 2015 Nov;25(8):661-73. doi: 10.1016/j.tcm.2015.02.005. Epub 2015 Feb 20. Trends Cardiovasc Med. 2015. PMID: 26001958 Review.
230 results