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Inhibition of Adenosine Monophosphate-Activated Protein Kinase-3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Signaling Leads to Hypercholesterolemia and Promotes Hepatic Steatosis and Insulin Resistance.
Loh K, Tam S, Murray-Segal L, Huynh K, Meikle PJ, Scott JW, van Denderen B, Chen Z, Steel R, LeBlond ND, Burkovsky LA, O'Dwyer C, Nunes JRC, Steinberg GR, Fullerton MD, Galic S, Kemp BE. Loh K, et al. Among authors: scott jw. Hepatol Commun. 2018 Nov 12;3(1):84-98. doi: 10.1002/hep4.1279. eCollection 2019 Jan. Hepatol Commun. 2018. PMID: 30619997 Free PMC article.
AMPK structure and regulation from three angles.
Kemp BE, Oakhill JS, Scott JW. Kemp BE, et al. Among authors: scott jw. Structure. 2007 Oct;15(10):1161-3. doi: 10.1016/j.str.2007.09.006. Structure. 2007. PMID: 17937905 Free article. No abstract available.
Structure and function of AMP-activated protein kinase.
Oakhill JS, Scott JW, Kemp BE. Oakhill JS, et al. Among authors: scott jw. Acta Physiol (Oxf). 2009 May;196(1):3-14. doi: 10.1111/j.1748-1716.2009.01977.x. Epub 2009 Feb 20. Acta Physiol (Oxf). 2009. PMID: 19245650 Review.
AMPK/SNF1 structure: a menage a trois of energy-sensing.
Scott JW, Oakhill JS, van Denderen BJ. Scott JW, et al. Front Biosci (Landmark Ed). 2009 Jan 1;14(2):596-610. doi: 10.2741/3266. Front Biosci (Landmark Ed). 2009. PMID: 19273088 Free article. Review.
Whole body deletion of AMP-activated protein kinase {beta}2 reduces muscle AMPK activity and exercise capacity.
Steinberg GR, O'Neill HM, Dzamko NL, Galic S, Naim T, Koopman R, Jørgensen SB, Honeyman J, Hewitt K, Chen ZP, Schertzer JD, Scott JW, Koentgen F, Lynch GS, Watt MJ, van Denderen BJ, Campbell DJ, Kemp BE. Steinberg GR, et al. Among authors: scott jw. J Biol Chem. 2010 Nov 26;285(48):37198-209. doi: 10.1074/jbc.M110.102434. Epub 2010 Sep 20. J Biol Chem. 2010. PMID: 20855892 Free PMC article.
AMPK is a direct adenylate charge-regulated protein kinase.
Oakhill JS, Steel R, Chen ZP, Scott JW, Ling N, Tam S, Kemp BE. Oakhill JS, et al. Among authors: scott jw. Science. 2011 Jun 17;332(6036):1433-5. doi: 10.1126/science.1200094. Science. 2011. PMID: 21680840
501 results