Schäfer A - Search Results

1

GADD45A binds R-loops and recruits TET1 to CpG island promoters.

Arab K, Karaulanov E, Musheev M, Trnka P, Schäfer A, Grummt I, Niehrs C. Arab K, et al. Among authors: schafer a. Nat Genet. 2019 Feb;51(2):217-223. doi: 10.1038/s41588-018-0306-6. Epub 2019 Jan 7. Nat Genet. 2019. PMID: 30617255 Free PMC article.

2

Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation.

Barreto G, Schäfer A, Marhold J, Stach D, Swaminathan SK, Handa V, Döderlein G, Maltry N, Wu W, Lyko F, Niehrs C. Barreto G, et al. Among authors: schafer a. Nature. 2007 Feb 8;445(7128):671-5. doi: 10.1038/nature05515. Epub 2007 Jan 31. Nature. 2007. PMID: 17268471

3

Ing1 functions in DNA demethylation by directing Gadd45a to H3K4me3.

Schäfer A, Karaulanov E, Stapf U, Döderlein G, Niehrs C. Schäfer A, et al. Genes Dev. 2013 Feb 1;27(3):261-73. doi: 10.1101/gad.186916.112. Genes Dev. 2013. PMID: 23388825 Free PMC article.

4

Long noncoding RNA TARID directs demethylation and activation of the tumor suppressor TCF21 via GADD45A.

Arab K, Park YJ, Lindroth AM, Schäfer A, Oakes C, Weichenhan D, Lukanova A, Lundin E, Risch A, Meister M, Dienemann H, Dyckhoff G, Herold-Mende C, Grummt I, Niehrs C, Plass C. Arab K, et al. Among authors: schafer a. Mol Cell. 2014 Aug 21;55(4):604-14. doi: 10.1016/j.molcel.2014.06.031. Epub 2014 Jul 31. Mol Cell. 2014. PMID: 25087872 Free article.

5

GADD45a physically and functionally interacts with TET1.

Kienhöfer S, Musheev MU, Stapf U, Helm M, Schomacher L, Niehrs C, Schäfer A. Kienhöfer S, et al. Among authors: schafer a. Differentiation. 2015 Jul-Oct;90(1-3):59-68. doi: 10.1016/j.diff.2015.10.003. Epub 2015 Nov 3. Differentiation. 2015. PMID: 26546041 Free PMC article.

6

TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of rRNA genes leading to active DNA demethylation.

Schmitz KM, Schmitt N, Hoffmann-Rohrer U, Schäfer A, Grummt I, Mayer C. Schmitz KM, et al. Among authors: schafer a. Mol Cell. 2009 Feb 13;33(3):344-53. doi: 10.1016/j.molcel.2009.01.015. Mol Cell. 2009. PMID: 19217408 Free article.

7

Gadd45a is an RNA binding protein and is localized in nuclear speckles.

Sytnikova YA, Kubarenko AV, Schäfer A, Weber AN, Niehrs C. Sytnikova YA, et al. Among authors: schafer a. PLoS One. 2011 Jan 7;6(1):e14500. doi: 10.1371/journal.pone.0014500. PLoS One. 2011. PMID: 21249130 Free PMC article.

8

Active DNA demethylation by Gadd45 and DNA repair.

Niehrs C, Schäfer A. Niehrs C, et al. Among authors: schafer a. Trends Cell Biol. 2012 Apr;22(4):220-7. doi: 10.1016/j.tcb.2012.01.002. Epub 2012 Feb 15. Trends Cell Biol. 2012. PMID: 22341196 Review.

9

Impaired DNA demethylation of C/EBP sites causes premature aging.

Schäfer A, Mekker B, Mallick M, Vastolo V, Karaulanov E, Sebastian D, von der Lippen C, Epe B, Downes DJ, Scholz C, Niehrs C. Schäfer A, et al. Genes Dev. 2018 Jun 1;32(11-12):742-762. doi: 10.1101/gad.311969.118. Epub 2018 Jun 8. Genes Dev. 2018. PMID: 29884649 Free PMC article.

10

Gadd45α modulates aversive learning through post-transcriptional regulation of memory-related mRNAs.

Aparisi Rey A, Karaulanov E, Sharopov S, Arab K, Schäfer A, Gierl M, Guggenhuber S, Brandes C, Pennella L, Gruhn WH, Jelinek R, Maul C, Conrad A, Kilb W, Luhmann HJ, Niehrs C, Lutz B. Aparisi Rey A, et al. Among authors: schafer a. EMBO Rep. 2019 Jun;20(6):e46022. doi: 10.15252/embr.201846022. Epub 2019 Apr 4. EMBO Rep. 2019. PMID: 30948457 Free PMC article.

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