Singh AP - Search Results

1

Pharmacophore Modeling, Synthesis, and Antibacterial Evaluation of Chalcones and Derivatives.

Zhang M, Prior AM, Maddox MM, Shen WJ, Hevener KE, Bruhn DF, Lee RB, Singh AP, Reinicke J, Simmons CJ, Hurdle JG, Lee RE, Sun D. Zhang M, et al. Among authors: singh ap. ACS Omega. 2018 Dec 31;3(12):18343-18360. doi: 10.1021/acsomega.8b03174. Epub 2018 Dec 26. ACS Omega. 2018. PMID: 30613820 Free PMC article.

2

Synthesis and antibacterial evaluation of macrocyclic diarylheptanoid derivatives.

Lin H, Bruhn DF, Maddox MM, Singh AP, Lee RE, Sun D. Lin H, et al. Among authors: singh ap. Bioorg Med Chem Lett. 2016 Aug 15;26(16):4070-6. doi: 10.1016/j.bmcl.2016.06.075. Epub 2016 Jun 27. Bioorg Med Chem Lett. 2016. PMID: 27406794 Free PMC article.

3

Chemical modulation of the biological activity of reutericyclin: a membrane-active antibiotic from Lactobacillus reuteri.

Cherian PT, Wu X, Maddox MM, Singh AP, Lee RE, Hurdle JG. Cherian PT, et al. Among authors: singh ap. Sci Rep. 2014 Apr 17;4:4721. doi: 10.1038/srep04721. Sci Rep. 2014. PMID: 24739957 Free PMC article.

4

Pentacyclic nitrofurans with in vivo efficacy and activity against nonreplicating Mycobacterium tuberculosis.

Rakesh, Bruhn DF, Scherman MS, Woolhiser LK, Madhura DB, Maddox MM, Singh AP, Lee RB, Hurdle JG, McNeil MR, Lenaerts AJ, Meibohm B, Lee RE. Rakesh, et al. Among authors: singh ap. PLoS One. 2014 Feb 5;9(2):e87909. doi: 10.1371/journal.pone.0087909. eCollection 2014. PLoS One. 2014. PMID: 24505329 Free PMC article.

5

Ureadepsipeptides as ClpP Activators.

Griffith EC, Zhao Y, Singh AP, Conlon BP, Tangallapally R, Shadrick WR, Liu J, Wallace MJ, Yang L, Elmore JM, Li Y, Zheng Z, Miller DJ, Cheramie MN, Lee RB, LaFleur MD, Lewis K, Lee RE. Griffith EC, et al. Among authors: singh ap. ACS Infect Dis. 2019 Nov 8;5(11):1915-1925. doi: 10.1021/acsinfecdis.9b00245. Epub 2019 Oct 24. ACS Infect Dis. 2019. PMID: 31588734 Free PMC article.

6

Aminomethyl spectinomycins as therapeutics for drug-resistant respiratory tract and sexually transmitted bacterial infections.

Bruhn DF, Waidyarachchi SL, Madhura DB, Shcherbakov D, Zheng Z, Liu J, Abdelrahman YM, Singh AP, Duscha S, Rathi C, Lee RB, Belland RJ, Meibohm B, Rosch JW, Böttger EC, Lee RE. Bruhn DF, et al. Among authors: singh ap. Sci Transl Med. 2015 May 20;7(288):288ra75. doi: 10.1126/scitranslmed.3010572. Sci Transl Med. 2015. PMID: 25995221 Free PMC article.

7

Synthesis and Evaluation of Thiazolidine Amide and N-Thiazolyl Amide Fluoroquinolone Derivatives.

Garza I, Wallace MJ, Fernando D, Singh A, Lee RE, Gerding JS, Franklin C, Yendapally R. Garza I, et al. Arch Pharm (Weinheim). 2017 Jun;350(6). doi: 10.1002/ardp.201700029. Epub 2017 Apr 21. Arch Pharm (Weinheim). 2017. PMID: 28429393

8

Gastrointestinal localization of metronidazole by a lactobacilli-inspired tetramic acid motif improves treatment outcomes in the hamster model of Clostridium difficile infection.

Cherian PT, Wu X, Yang L, Scarborough JS, Singh AP, Alam ZA, Lee RE, Hurdle JG. Cherian PT, et al. Among authors: singh ap. J Antimicrob Chemother. 2015 Nov;70(11):3061-9. doi: 10.1093/jac/dkv231. Epub 2015 Aug 18. J Antimicrob Chemother. 2015. PMID: 26286574 Free PMC article.

9

Synthesis and evaluation of pretomanid (PA-824) oxazolidinone hybrids.

Rakesh, Bruhn DF, Scherman MS, Singh AP, Yang L, Liu J, Lenaerts AJ, Lee RE. Rakesh, et al. Among authors: singh ap. Bioorg Med Chem Lett. 2016 Jan 15;26(2):388-391. doi: 10.1016/j.bmcl.2015.12.002. Epub 2015 Dec 7. Bioorg Med Chem Lett. 2016. PMID: 26711150 Free PMC article.

10

In Vivo and In Vitro Effects of a ClpP-Activating Antibiotic against Vancomycin-Resistant Enterococci.

Brown Gandt A, Griffith EC, Lister IM, Billings LL, Han A, Tangallapally R, Zhao Y, Singh AP, Lee RE, LaFleur MD. Brown Gandt A, et al. Among authors: singh ap. Antimicrob Agents Chemother. 2018 Jul 27;62(8):e00424-18. doi: 10.1128/AAC.00424-18. Print 2018 Aug. Antimicrob Agents Chemother. 2018. PMID: 29784838 Free PMC article.

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