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First-in-human study assessing safety, tolerability, and pharmacokinetics of 2-hydroxybenzylamine acetate, a selective dicarbonyl electrophile scavenger, in healthy volunteers.
Pitchford LM, Rathmacher JA, Fuller JC Jr, Daniels JS, Morrison RD, Akers WS, Abumrad NN, Amarnath V, Currey PM, Roberts LJ, Oates JA, Boutaud O. Pitchford LM, et al. BMC Pharmacol Toxicol. 2019 Jan 5;20(1):1. doi: 10.1186/s40360-018-0281-7. BMC Pharmacol Toxicol. 2019. PMID: 30611293 Free PMC article. Clinical Trial.
In vitro safety pharmacology evaluation of 2-hydroxybenzylamine acetate.
Fuller JC Jr, Pitchford LM, Morrison RD, Daniels JS, Flynn CR, Abumrad NN, Oates JA, Boutaud O, Rathmacher JA. Fuller JC Jr, et al. Among authors: pitchford lm. Food Chem Toxicol. 2018 Nov;121:541-548. doi: 10.1016/j.fct.2018.09.047. Epub 2018 Sep 22. Food Chem Toxicol. 2018. PMID: 30253245 Free PMC article.
Safety, tolerability, and pharmacokinetics of repeated oral doses of 2-hydroxybenzylamine acetate in healthy volunteers: a double-blind, randomized, placebo-controlled clinical trial.
Pitchford LM, Driver PM, Fuller JC Jr, Akers WS, Abumrad NN, Amarnath V, Milne GL, Chen SC, Ye F, Roberts LJ 2nd, Shoemaker MB, Oates JA, Rathmacher JA, Boutaud O. Pitchford LM, et al. BMC Pharmacol Toxicol. 2020 Jan 6;21(1):3. doi: 10.1186/s40360-020-0382-y. BMC Pharmacol Toxicol. 2020. PMID: 31907026 Free PMC article. Clinical Trial.
Long-term Effects of Calcium β-Hydroxy-β-Methylbutyrate and Vitamin D3 Supplementation on Muscular Function in Older Adults With and Without Resistance Training: A Randomized, Double-blind, Controlled Study.
Rathmacher JA, Pitchford LM, Khoo P, Angus H, Lang J, Lowry K, Ruby C, Krajek AC, Fuller JC, Sharp RL. Rathmacher JA, et al. Among authors: pitchford lm. J Gerontol A Biol Sci Med Sci. 2020 Oct 15;75(11):2089-2097. doi: 10.1093/gerona/glaa218. J Gerontol A Biol Sci Med Sci. 2020. PMID: 32857128 Free PMC article. Clinical Trial.
2-Hydroxybenzylamine (2-HOBA) to prevent early recurrence of atrial fibrillation after catheter ablation: protocol for a randomized controlled trial including detection of AF using a wearable device.
O'Neill MJ, Yoneda ZT, Crawford DM, Ye F, Ao M, Pitchford LM, Rathmacher JA, Murray KT, Akers WS, Roden DM, Michaud GF, Shoemaker MB. O'Neill MJ, et al. Among authors: pitchford lm. Trials. 2021 Aug 28;22(1):576. doi: 10.1186/s13063-021-05553-6. Trials. 2021. PMID: 34454591 Free PMC article.
17 results