Bolton JL - Search Results

1

The Multiple Biological Targets of Hops and Bioactive Compounds.

Bolton JL, Dunlap TL, Hajirahimkhan A, Mbachu O, Chen SN, Chadwick L, Nikolic D, van Breemen RB, Pauli GF, Dietz BM. Bolton JL, et al. Chem Res Toxicol. 2019 Feb 18;32(2):222-233. doi: 10.1021/acs.chemrestox.8b00345. Epub 2019 Jan 22. Chem Res Toxicol. 2019. PMID: 30608650 Free PMC article. Review.

2

Screening drugs for metabolic stability using pulsed ultrafiltration mass spectrometry.

Geun Shin Y, Bolton JL, van Breemen RB. Geun Shin Y, et al. Among authors: bolton jl. Comb Chem High Throughput Screen. 2002 Feb;5(1):59-64. doi: 10.2174/1386207023330633. Comb Chem High Throughput Screen. 2002. PMID: 11860340

3

Oxidative DNA damage induced by equine estrogen metabolites: role of estrogen receptor alpha.

Liu X, Yao J, Pisha E, Yang Y, Hua Y, van Breemen RB, Bolton JL. Liu X, et al. Among authors: bolton jl. Chem Res Toxicol. 2002 Apr;15(4):512-9. doi: 10.1021/tx0101649. Chem Res Toxicol. 2002. PMID: 11952337

4

Black cohosh (Cimicifuga racemosa L.) protects against menadione-induced DNA damage through scavenging of reactive oxygen species: bioassay-directed isolation and characterization of active principles.

Burdette JE, Chen SN, Lu ZZ, Xu H, White BE, Fabricant DS, Liu J, Fong HH, Farnsworth NR, Constantinou AI, Van Breemen RB, Pezzuto JM, Bolton JL. Burdette JE, et al. Among authors: bolton jl. J Agric Food Chem. 2002 Nov 20;50(24):7022-8. doi: 10.1021/jf020725h. J Agric Food Chem. 2002. PMID: 12428954

5

Catechol estrogen 4-hydroxyequilenin is a substrate and an inhibitor of catechol-O-methyltransferase.

Yao J, Li Y, Chang M, Wu H, Yang X, Goodman JE, Liu X, Liu H, Mesecar AD, Van Breemen RB, Yager JD, Bolton JL. Yao J, et al. Among authors: bolton jl. Chem Res Toxicol. 2003 May;16(5):668-75. doi: 10.1021/tx0340549. Chem Res Toxicol. 2003. PMID: 12755597

6

Identification of novel electrophilic metabolites of piper methysticum Forst (Kava).

Johnson BM, Qiu SX, Zhang S, Zhang F, Burdette JE, Yu L, Bolton JL, van Breemen RB. Johnson BM, et al. Among authors: bolton jl. Chem Res Toxicol. 2003 Jun;16(6):733-40. doi: 10.1021/tx020113r. Chem Res Toxicol. 2003. PMID: 12807356

7

Effect of halogenated substituents on the metabolism and estrogenic effects of the equine estrogen, equilenin.

Liu X, Zhang F, Liu H, Burdette JE, Li Y, Overk CR, Pisha E, Yao J, van Breemen RB, Swanson SM, Bolton JL. Liu X, et al. Among authors: bolton jl. Chem Res Toxicol. 2003 Jun;16(6):741-9. doi: 10.1021/tx030001f. Chem Res Toxicol. 2003. PMID: 12807357

8

Black cohosh acts as a mixed competitive ligand and partial agonist of the serotonin receptor.

Burdette JE, Liu J, Chen SN, Fabricant DS, Piersen CE, Barker EL, Pezzuto JM, Mesecar A, Van Breemen RB, Farnsworth NR, Bolton JL. Burdette JE, et al. Among authors: bolton jl. J Agric Food Chem. 2003 Sep 10;51(19):5661-70. doi: 10.1021/jf034264r. J Agric Food Chem. 2003. PMID: 12952416

9

Equine catechol estrogen 4-hydroxyequilenin is a more potent inhibitor of the variant form of catechol-O-methyltransferase.

Li Y, Yao J, Chang M, Nikolic D, Yu L, Yager JD, Mesecar AD, van Breemen RB, Bolton JL. Li Y, et al. Among authors: bolton jl. Chem Res Toxicol. 2004 Apr;17(4):512-20. doi: 10.1021/tx0342464. Chem Res Toxicol. 2004. PMID: 15089093

10

Oxidation of raloxifene to quinoids: potential toxic pathways via a diquinone methide and o-quinones.

Yu L, Liu H, Li W, Zhang F, Luckie C, van Breemen RB, Thatcher GR, Bolton JL. Yu L, et al. Among authors: bolton jl. Chem Res Toxicol. 2004 Jul;17(7):879-88. doi: 10.1021/tx0342722. Chem Res Toxicol. 2004. PMID: 15257612

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