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Optimization of N-benzyl-5-nitrofuran-2-carboxamide as an antitubercular agent.
Gallardo-Macias R, Kumar P, Jaskowski M, Richmann T, Shrestha R, Russo R, Singleton E, Zimmerman MD, Ho HP, Dartois V, Connell N, Alland D, Freundlich JS. Gallardo-Macias R, et al. Among authors: singleton e. Bioorg Med Chem Lett. 2019 Feb 15;29(4):601-606. doi: 10.1016/j.bmcl.2018.12.053. Epub 2018 Dec 24. Bioorg Med Chem Lett. 2019. PMID: 30600207 Free PMC article.
Susceptibility of Select Agents to Predation by Predatory Bacteria.
Russo R, Chae R, Mukherjee S, Singleton EJ, Occi JL, Kadouri DE, Connell ND. Russo R, et al. Among authors: singleton ej. Microorganisms. 2015 Dec 2;3(4):903-12. doi: 10.3390/microorganisms3040903. Microorganisms. 2015. PMID: 27682124 Free PMC article.
Predatory Bacteria Attenuate Klebsiella pneumoniae Burden in Rat Lungs.
Shatzkes K, Singleton E, Tang C, Zuena M, Shukla S, Gupta S, Dharani S, Onyile O, Rinaggio J, Connell ND, Kadouri DE. Shatzkes K, et al. Among authors: singleton e. mBio. 2016 Nov 8;7(6):e01847-16. doi: 10.1128/mBio.01847-16. mBio. 2016. PMID: 27834203 Free PMC article.
A Novel Small-Molecule Inhibitor of the Mycobacterium tuberculosis Demethylmenaquinone Methyltransferase MenG Is Bactericidal to Both Growing and Nutritionally Deprived Persister Cells.
Sukheja P, Kumar P, Mittal N, Li SG, Singleton E, Russo R, Perryman AL, Shrestha R, Awasthi D, Husain S, Soteropoulos P, Brukh R, Connell N, Freundlich JS, Alland D. Sukheja P, et al. Among authors: singleton e. mBio. 2017 Feb 14;8(1):e02022-16. doi: 10.1128/mBio.02022-16. mBio. 2017. PMID: 28196957 Free PMC article.
Effect of predatory bacteria on the gut bacterial microbiota in rats.
Shatzkes K, Tang C, Singleton E, Shukla S, Zuena M, Gupta S, Dharani S, Rinaggio J, Connell ND, Kadouri DE. Shatzkes K, et al. Among authors: singleton e. Sci Rep. 2017 Mar 6;7:43483. doi: 10.1038/srep43483. Sci Rep. 2017. PMID: 28262674 Free PMC article.
Rapid Detection of Bacillus anthracis Bloodstream Infections by Use of a Novel Assay in the GeneXpert System.
Banada PP, Deshpande S, Russo R, Singleton E, Shah D, Patel B, Burday M, Koshy R, Wang Q, Jones M, Gall A, Lokhov S, Kwiatkowski R, Persing D, Connell N, Alland D. Banada PP, et al. Among authors: singleton e. J Clin Microbiol. 2017 Oct;55(10):2964-2971. doi: 10.1128/JCM.00466-17. Epub 2017 Jul 26. J Clin Microbiol. 2017. PMID: 28747367 Free PMC article.
Addressing the Metabolic Stability of Antituberculars through Machine Learning.
Stratton TP, Perryman AL, Vilchèze C, Russo R, Li SG, Patel JS, Singleton E, Ekins S, Connell N, Jacobs WR Jr, Freundlich JS. Stratton TP, et al. Among authors: singleton e. ACS Med Chem Lett. 2017 Sep 14;8(10):1099-1104. doi: 10.1021/acsmedchemlett.7b00299. eCollection 2017 Oct 12. ACS Med Chem Lett. 2017. PMID: 29057058 Free PMC article.
Novel Pyrimidines as Antitubercular Agents.
Inoyama D, Paget SD, Russo R, Kandasamy S, Kumar P, Singleton E, Occi J, Tuckman M, Zimmerman MD, Ho HP, Perryman AL, Dartois V, Connell N, Freundlich JS. Inoyama D, et al. Among authors: singleton e. Antimicrob Agents Chemother. 2018 Feb 23;62(3):e02063-17. doi: 10.1128/AAC.02063-17. Print 2018 Mar. Antimicrob Agents Chemother. 2018. PMID: 29311070 Free PMC article.
Naïve Bayesian Models for Vero Cell Cytotoxicity.
Perryman AL, Patel JS, Russo R, Singleton E, Connell N, Ekins S, Freundlich JS. Perryman AL, et al. Among authors: singleton e. Pharm Res. 2018 Jun 29;35(9):170. doi: 10.1007/s11095-018-2439-9. Pharm Res. 2018. PMID: 29959603 Free PMC article.
237 results