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De Novo Mutations Affecting the Catalytic Cα Subunit of PP2A, PPP2CA, Cause Syndromic Intellectual Disability Resembling Other PP2A-Related Neurodevelopmental Disorders.
Reynhout S, Jansen S, Haesen D, van Belle S, de Munnik SA, Bongers EMHF, Schieving JH, Marcelis C, Amiel J, Rio M, Mclaughlin H, Ladda R, Sell S, Kriek M, Peeters-Scholte CMPCD, Terhal PA, van Gassen KL, Verbeek N, Henry S, Scott Schwoerer J, Malik S, Revencu N, Ferreira CR, Macnamara E, Braakman HMH, Brimble E, Ruzhnikov MRZ, Wagner M, Harrer P, Wieczorek D, Kuechler A, Tziperman B, Barel O, de Vries BBA, Gordon CT, Janssens V, Vissers LELM. Reynhout S, et al. Among authors: janssens v. Am J Hum Genet. 2019 Jan 3;104(1):139-156. doi: 10.1016/j.ajhg.2018.12.002. Epub 2018 Dec 27. Am J Hum Genet. 2019. PMID: 30595372 Free PMC article.
The Basic Biology of PP2A in Hematologic Cells and Malignancies.
Haesen D, Sents W, Lemaire K, Hoorne Y, Janssens V. Haesen D, et al. Among authors: janssens v. Front Oncol. 2014 Dec 11;4:347. doi: 10.3389/fonc.2014.00347. eCollection 2014. Front Oncol. 2014. PMID: 25566494 Free PMC article. Review.
B56δ-related protein phosphatase 2A dysfunction identified in patients with intellectual disability.
Houge G, Haesen D, Vissers LE, Mehta S, Parker MJ, Wright M, Vogt J, McKee S, Tolmie JL, Cordeiro N, Kleefstra T, Willemsen MH, Reijnders MR, Berland S, Hayman E, Lahat E, Brilstra EH, van Gassen KL, Zonneveld-Huijssoon E, de Bie CI, Hoischen A, Eichler EE, Holdhus R, Steen VM, Døskeland SO, Hurles ME, FitzPatrick DR, Janssens V. Houge G, et al. Among authors: janssens v. J Clin Invest. 2015 Aug 3;125(8):3051-62. doi: 10.1172/JCI79860. Epub 2015 Jul 13. J Clin Invest. 2015. PMID: 26168268 Free PMC article.
PP2A Inactivation Mediated by PPP2R4 Haploinsufficiency Promotes Cancer Development.
Sents W, Meeusen B, Kalev P, Radaelli E, Sagaert X, Miermans E, Haesen D, Lambrecht C, Dewerchin M, Carmeliet P, Westermarck J, Sablina A, Janssens V. Sents W, et al. Among authors: janssens v. Cancer Res. 2017 Dec 15;77(24):6825-6837. doi: 10.1158/0008-5472.CAN-16-2911. Epub 2017 Oct 18. Cancer Res. 2017. PMID: 29046336
Physiologic functions of PP2A: Lessons from genetically modified mice.
Reynhout S, Janssens V. Reynhout S, et al. Among authors: janssens v. Biochim Biophys Acta Mol Cell Res. 2019 Jan;1866(1):31-50. doi: 10.1016/j.bbamcr.2018.07.010. Epub 2018 Jul 18. Biochim Biophys Acta Mol Cell Res. 2019. PMID: 30030003 Free article. Review.
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