Fascione M - Search Results

1

The characterisation of a galactokinase from Streptomyces coelicolor.

Keenan T, Mills R, Pocock E, Budhadev D, Parmeggiani F, Flitsch S, Fascione M. Keenan T, et al. Among authors: fascione m. Carbohydr Res. 2019 Jan 15;472:132-137. doi: 10.1016/j.carres.2018.12.005. Epub 2018 Dec 14. Carbohydr Res. 2019. PMID: 30593944 Free article.

2

Site-selective C-C modification of proteins at neutral pH using organocatalyst-mediated cross aldol ligations.

Spears RJ, Brabham RL, Budhadev D, Keenan T, McKenna S, Walton J, Brannigan JA, Brzozowski AM, Wilkinson AJ, Plevin M, Fascione MA. Spears RJ, et al. Among authors: fascione ma. Chem Sci. 2018 May 31;9(25):5585-5593. doi: 10.1039/c8sc01617h. eCollection 2018 Jul 7. Chem Sci. 2018. PMID: 30061990 Free PMC article.

3

Using automated glycan assembly (AGA) for the practical synthesis of heparan sulfate oligosaccharide precursors.

Budhadev D, Saxby K, Walton J, Davies G, Tyler PC, Schwörer R, Fascione MA. Budhadev D, et al. Org Biomol Chem. 2019 Feb 13;17(7):1817-1821. doi: 10.1039/c8ob02756k. Org Biomol Chem. 2019. PMID: 30543331 Free article.

4

Chemoenzymatic synthesis of 3-deoxy-3-fluoro-l-fucose and its enzymatic incorporation into glycoconjugates.

Valverde P, Vendeville JB, Hollingsworth K, Mattey AP, Keenan T, Chidwick H, Ledru H, Huonnic K, Huang K, Light ME, Turner N, Jiménez-Barbero J, Galan MC, Fascione MA, Flitsch S, Turnbull WB, Linclau B. Valverde P, et al. Among authors: fascione ma. Chem Commun (Camb). 2020 Jun 11;56(47):6408-6411. doi: 10.1039/d0cc02209h. Chem Commun (Camb). 2020. PMID: 32390019

5

Rapid sodium periodate cleavage of an unnatural amino acid enables unmasking of a highly reactive α-oxo aldehyde for protein bioconjugation.

Brabham RL, Keenan T, Husken A, Bilsborrow J, McBerney R, Kumar V, Turnbull WB, Fascione MA. Brabham RL, et al. Org Biomol Chem. 2020 Jun 7;18(21):4000-4003. doi: 10.1039/d0ob00972e. Epub 2020 May 19. Org Biomol Chem. 2020. PMID: 32427272 Free article.

6

Profiling Substrate Promiscuity of Wild-Type Sugar Kinases for Multi-fluorinated Monosaccharides.

Keenan T, Parmeggiani F, Malassis J, Fontenelle CQ, Vendeville JB, Offen W, Both P, Huang K, Marchesi A, Heyam A, Young C, Charnock SJ, Davies GJ, Linclau B, Flitsch SL, Fascione MA. Keenan T, et al. Cell Chem Biol. 2020 Sep 17;27(9):1199-1206.e5. doi: 10.1016/j.chembiol.2020.06.005. Epub 2020 Jul 2. Cell Chem Biol. 2020. PMID: 32619452 Free article.

7

Correction: Rapid sodium periodate cleavage of an unnatural amino acid enables unmasking of a highly reactive α-oxo aldehyde for protein bioconjugation.

Brabham RL, Keenan T, Husken A, Bilsborrow J, McBerney R, Kumar V, Turnbull WB, Fascione MA. Brabham RL, et al. Org Biomol Chem. 2020 Aug 5;18(30):5982. doi: 10.1039/d0ob90100h. Org Biomol Chem. 2020. PMID: 32706355 Free article.

8

Reconstitution and optimisation of the biosynthesis of bacterial sugar pseudaminic acid (Pse5Ac7Ac) enables preparative enzymatic synthesis of CMP-Pse5Ac7Ac.

Chidwick HS, Flack EKP, Keenan T, Walton J, Thomas GH, Fascione MA. Chidwick HS, et al. Sci Rep. 2021 Feb 26;11(1):4756. doi: 10.1038/s41598-021-83707-x. Sci Rep. 2021. PMID: 33637817 Free PMC article.

9

Introducing affinity and selectivity into galectin-targeting nanoparticles with fluorinated glycan ligands.

Richards SJ, Keenan T, Vendeville JB, Wheatley DE, Chidwick H, Budhadev D, Council CE, Webster CS, Ledru H, Baker AN, Walker M, Galan MC, Linclau B, Fascione MA, Gibson MI. Richards SJ, et al. Among authors: fascione ma. Chem Sci. 2020 Nov 16;12(3):905-910. doi: 10.1039/d0sc05360k. Chem Sci. 2020. PMID: 34163856 Free PMC article.

10

A Tale of Two Bioconjugations: pH Controlled Divergent Reactivity of Protein α-oxo-Aldehydes in Competing α-oxo-Mannich and Catalyst-Free Aldol Ligations.

Keenan T, Spears RJ, Akkad S, Mahon CS, Hatton NE, Walton J, Noble A, Yates ND, Baumann CG, Parkin A, Signoret N, Fascione MA. Keenan T, et al. ACS Chem Biol. 2021 Nov 19;16(11):2387-2400. doi: 10.1021/acschembio.1c00531. Epub 2021 Nov 9. ACS Chem Biol. 2021. PMID: 34751550 Free article.

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