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Efficacy and safety of the dual SYK/JAK inhibitor cerdulatinib in patients with relapsed or refractory B-cell malignancies: Results of a phase I study.
Hamlin PA, Flinn IW, Wagner-Johnston N, Burger JA, Coffey GP, Conley PB, Michelson G, Leeds JM, Der K, Kim Y, Sabalvaro-Torres A, Birrell M, Pandey A, Curnutte JT, Patel MR. Hamlin PA, et al. Among authors: birrell m. Am J Hematol. 2019 Apr;94(4):E90-E93. doi: 10.1002/ajh.25387. Epub 2019 Jan 8. Am J Hematol. 2019. PMID: 30592080 Free article. Clinical Trial. No abstract available.
Cerdulatinib Pharmacodynamics and Relationships to Tumor Response Following Oral Dosing in Patients with Relapsed/Refractory B-cell Malignancies.
Coffey GP, Feng J, Betz A, Pandey A, Birrell M, Leeds JM, Der K, Kadri S, Lu P, Segal J, Wang YL, Michelson G, Curnutte JT, Conley PB. Coffey GP, et al. Among authors: birrell m. Clin Cancer Res. 2019 Feb 15;25(4):1174-1184. doi: 10.1158/1078-0432.CCR-18-1047. Epub 2018 Oct 17. Clin Cancer Res. 2019. PMID: 30333224 Clinical Trial.
PI3Kγδ inhibition suppresses key disease features in a rat model of asthma.
Pinkerton JW, Preite S, Piras A, Zervas D, Markou T, Freeman MS, Hofving T, Ivarsson E, Bonvini SJ, Brailsford W, Yrlid L, Belvisi MG, Birrell MA. Pinkerton JW, et al. Among authors: birrell ma. Respir Res. 2024 Apr 23;25(1):175. doi: 10.1186/s12931-024-02814-1. Respir Res. 2024. PMID: 38654248 Free PMC article.
Characterization of Selective and Potent JAK1 Inhibitors Intended for the Inhaled Treatment of Asthma.
Nilsson M, Rhedin M, Hendrickx R, Berglund S, Piras A, Blomgran P, Cavallin A, Collins M, Dahl G, Dekkak B, Ericsson T, Hagberg N, Holmberg AA, Leffler A, Lundqvist AJ, Markou T, Pinkerton J, Rönnblom L, Siu S, Taylor V, Wennberg T, Zervas D, Laurence ADJ, Mitra S, Belvisi MG, Birrell M, Borde A. Nilsson M, et al. Among authors: birrell m. Drug Des Devel Ther. 2022 Aug 31;16:2901-2917. doi: 10.2147/DDDT.S354291. eCollection 2022. Drug Des Devel Ther. 2022. PMID: 36068788 Free PMC article.
COVID-MATCH65-A prospectively derived clinical decision rule for severe acute respiratory syndrome coronavirus 2.
Trubiano JA, Vogrin S, Smibert OC, Marhoon N, Alexander AA, Chua KYL, James FL, Jones NRL, Grigg SE, Xu CLH, Moini N, Stanley SR, Birrell MT, Rose MT, Gordon CL, Kwong JC, Holmes NE. Trubiano JA, et al. Among authors: birrell mt. PLoS One. 2020 Dec 9;15(12):e0243414. doi: 10.1371/journal.pone.0243414. eCollection 2020. PLoS One. 2020. PMID: 33296409 Free PMC article.
120 results