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Tumor cell escape from therapy-induced senescence.
Saleh T, Tyutyunyk-Massey L, Murray GF, Alotaibi MR, Kawale AS, Elsayed Z, Henderson SC, Yakovlev V, Elmore LW, Toor A, Harada H, Reed J, Landry JW, Gewirtz DA. Saleh T, et al. Among authors: harada h. Biochem Pharmacol. 2019 Apr;162:202-212. doi: 10.1016/j.bcp.2018.12.013. Epub 2018 Dec 19. Biochem Pharmacol. 2019. PMID: 30576620
Yet another function of p53--the switch that determines whether radiation-induced autophagy will be cytoprotective or nonprotective: implications for autophagy inhibition as a therapeutic strategy.
Chakradeo S, Sharma K, Alhaddad A, Bakhshwin D, Le N, Harada H, Nakajima W, Yeudall WA, Torti SV, Torti FM, Gewirtz DA. Chakradeo S, et al. Among authors: harada h. Mol Pharmacol. 2015 May;87(5):803-14. doi: 10.1124/mol.114.095273. Epub 2015 Feb 9. Mol Pharmacol. 2015. PMID: 25667224 Free PMC article.
NOXA expression is downregulated in human breast cancer undergoing incomplete pathological response and senescence after neoadjuvant chemotherapy.
Al Shboul S, El-Sadoni M, Alhesa A, Abu Shahin N, Abuquteish D, Abu Al Karsaneh O, Alsharaiah E, Ismail MA, Tyutyunyk-Massey L, Alotaibi MR, Neely V, Harada H, Saleh T. Al Shboul S, et al. Among authors: harada h. Sci Rep. 2023 Sep 23;13(1):15903. doi: 10.1038/s41598-023-42994-2. Sci Rep. 2023. PMID: 37741850 Free PMC article.
The Combination of Radiation with PARP Inhibition Enhances Senescence and Sensitivity to the Senolytic, Navitoclax, in Triple Negative Breast Tumor Cells.
Softah A, Alotaibi MR, Alhoshani AR, Saleh T, Alhazzani K, Almutairi MM, AlRowis R, Alshehri S, Albekairy NA, Harada H, Boyd R, Chakraborty E, Gewirtz DA, As Sobeai HM. Softah A, et al. Among authors: harada h. Biomedicines. 2023 Nov 16;11(11):3066. doi: 10.3390/biomedicines11113066. Biomedicines. 2023. PMID: 38002066 Free PMC article.
2,624 results