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A Wars2 Mutant Mouse Model Displays OXPHOS Deficiencies and Activation of Tissue-Specific Stress Response Pathways.
Agnew T, Goldsworthy M, Aguilar C, Morgan A, Simon M, Hilton H, Esapa C, Wu Y, Cater H, Bentley L, Scudamore C, Poulton J, Morten KJ, Thompson K, He L, Brown SDM, Taylor RW, Bowl MR, Cox RD. Agnew T, et al. Among authors: cox rd. Cell Rep. 2018 Dec 18;25(12):3315-3328.e6. doi: 10.1016/j.celrep.2018.11.080. Cell Rep. 2018. PMID: 30566859 Free PMC article.
Novel phenotypes identified by plasma biochemical screening in the mouse.
Hough TA, Nolan PM, Tsipouri V, Toye AA, Gray IC, Goldsworthy M, Moir L, Cox RD, Clements S, Glenister PH, Wood J, Selley RL, Strivens MA, Vizor L, McCormack SL, Peters J, Fisher EM, Spurr N, Rastan S, Martin JE, Brown SD, Hunter AJ. Hough TA, et al. Among authors: cox rd. Mamm Genome. 2002 Oct;13(10):595-602. doi: 10.1007/s00335-002-2188-1. Mamm Genome. 2002. PMID: 12420138
Rodent models of genetic disease.
Cox RD, Brown SD. Cox RD, et al. Curr Opin Genet Dev. 2003 Jun;13(3):278-83. doi: 10.1016/s0959-437x(03)00051-0. Curr Opin Genet Dev. 2003. PMID: 12787790 Review.
New semidominant mutations that affect mouse development.
Bogani D, Warr N, Elms P, Davies J, Tymowska-Lalanne Z, Goldsworthy M, Cox RD, Keays DA, Flint J, Wilson V, Nolan P, Arkell R. Bogani D, et al. Among authors: cox rd. Genesis. 2004 Oct;40(2):109-117. doi: 10.1002/gene.20071. Genesis. 2004. PMID: 15384171
ENU mutagenesis, a way forward to understand gene function.
Acevedo-Arozena A, Wells S, Potter P, Kelly M, Cox RD, Brown SD. Acevedo-Arozena A, et al. Among authors: cox rd. Annu Rev Genomics Hum Genet. 2008;9:49-69. doi: 10.1146/annurev.genom.9.081307.164224. Annu Rev Genomics Hum Genet. 2008. PMID: 18949851 Review.
Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic beta cells recapitulates neonatal diabetes.
Girard CA, Wunderlich FT, Shimomura K, Collins S, Kaizik S, Proks P, Abdulkader F, Clark A, Ball V, Zubcevic L, Bentley L, Clark R, Church C, Hugill A, Galvanovskis J, Cox R, Rorsman P, Brüning JC, Ashcroft FM. Girard CA, et al. J Clin Invest. 2009 Jan;119(1):80-90. doi: 10.1172/JCI35772. Epub 2008 Dec 8. J Clin Invest. 2009. PMID: 19065048 Free PMC article.
206 results