Nooka AK - Search Results

1

Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia.

Tron AE, Belmonte MA, Adam A, Aquila BM, Boise LH, Chiarparin E, Cidado J, Embrey KJ, Gangl E, Gibbons FD, Gregory GP, Hargreaves D, Hendricks JA, Johannes JW, Johnstone RW, Kazmirski SL, Kettle JG, Lamb ML, Matulis SM, Nooka AK, Packer MJ, Peng B, Rawlins PB, Robbins DW, Schuller AG, Su N, Yang W, Ye Q, Zheng X, Secrist JP, Clark EA, Wilson DM, Fawell SE, Hird AW. Tron AE, et al. Among authors: nooka ak. Nat Commun. 2018 Dec 17;9(1):5341. doi: 10.1038/s41467-018-07551-w. Nat Commun. 2018. PMID: 30559424 Free PMC article.

2

Sequential or combination therapy for multiple myeloma.

Nooka A, Lonial S. Nooka A, et al. Expert Rev Hematol. 2012 Oct;5(5):533-45. doi: 10.1586/ehm.12.49. Expert Rev Hematol. 2012. PMID: 23146057 Review.

3

Bortezomib-containing induction regimens in transplant-eligible myeloma patients: a meta-analysis of phase 3 randomized clinical trials.

Nooka AK, Kaufman JL, Behera M, Langston A, Waller EK, Flowers CR, Gleason C, Boise LH, Lonial S. Nooka AK, et al. Cancer. 2013 Dec 1;119(23):4119-28. doi: 10.1002/cncr.28325. Epub 2013 Sep 4. Cancer. 2013. PMID: 24005889 Free article. Clinical Trial.

4

Consolidation and maintenance therapy with lenalidomide, bortezomib and dexamethasone (RVD) in high-risk myeloma patients.

Nooka AK, Kaufman JL, Muppidi S, Langston A, Heffner LT, Gleason C, Casbourne D, Saxe D, Boise LH, Lonial S. Nooka AK, et al. Leukemia. 2014 Mar;28(3):690-3. doi: 10.1038/leu.2013.335. Epub 2013 Nov 13. Leukemia. 2014. PMID: 24220275

5

In Silico Modeling-based Identification of Glucose Transporter 4 (GLUT4)-selective Inhibitors for Cancer Therapy.

Mishra RK, Wei C, Hresko RC, Bajpai R, Heitmeier M, Matulis SM, Nooka AK, Rosen ST, Hruz PW, Schiltz GE, Shanmugam M. Mishra RK, et al. Among authors: nooka ak. J Biol Chem. 2015 Jun 5;290(23):14441-53. doi: 10.1074/jbc.M114.628826. Epub 2015 Apr 6. J Biol Chem. 2015. PMID: 25847249 Free PMC article.

6

Targeting glutamine metabolism in multiple myeloma enhances BIM binding to BCL-2 eliciting synthetic lethality to venetoclax.

Bajpai R, Matulis SM, Wei C, Nooka AK, Von Hollen HE, Lonial S, Boise LH, Shanmugam M. Bajpai R, et al. Among authors: nooka ak. Oncogene. 2016 Jul 28;35(30):3955-64. doi: 10.1038/onc.2015.464. Epub 2015 Dec 7. Oncogene. 2016. PMID: 26640142 Free PMC article.

7

Dexamethasone treatment promotes Bcl-2 dependence in multiple myeloma resulting in sensitivity to venetoclax.

Matulis SM, Gupta VA, Nooka AK, Hollen HV, Kaufman JL, Lonial S, Boise LH. Matulis SM, et al. Among authors: nooka ak. Leukemia. 2016 May;30(5):1086-93. doi: 10.1038/leu.2015.350. Epub 2015 Dec 28. Leukemia. 2016. PMID: 26707935 Free PMC article.

8

BCL2-BH4 antagonist BDA-366 suppresses human myeloma growth.

Deng J, Park D, Wang M, Nooka A, Deng Q, Matulis S, Kaufman J, Lonial S, Boise LH, Galipeau J, Deng X. Deng J, et al. Oncotarget. 2016 May 10;7(19):27753-63. doi: 10.18632/oncotarget.8513. Oncotarget. 2016. PMID: 27049723 Free PMC article.

9

Dual inhibition of Mcl-1 by the combination of carfilzomib and TG02 in multiple myeloma.

Ponder KG, Matulis SM, Hitosugi S, Gupta VA, Sharp C, Burrows F, Nooka AK, Kaufman JL, Lonial S, Boise LH. Ponder KG, et al. Among authors: nooka ak. Cancer Biol Ther. 2016 Jul 2;17(7):769-77. doi: 10.1080/15384047.2016.1192086. Cancer Biol Ther. 2016. PMID: 27246906 Free PMC article.

10

Bortezomib-induced heat shock response protects multiple myeloma cells and is activated by heat shock factor 1 serine 326 phosphorylation.

Shah SP, Nooka AK, Jaye DL, Bahlis NJ, Lonial S, Boise LH. Shah SP, et al. Among authors: nooka ak. Oncotarget. 2016 Sep 13;7(37):59727-59741. doi: 10.18632/oncotarget.10847. Oncotarget. 2016. PMID: 27487129 Free PMC article.

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