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Stabilization of cytokine mRNAs in iNKT cells requires the serine-threonine kinase IRE1alpha.
Govindarajan S, Gaublomme D, Van der Cruyssen R, Verheugen E, Van Gassen S, Saeys Y, Tavernier S, Iwawaki T, Bloch Y, Savvides SN, Lambrecht BN, Janssens S, Elewaut D, Drennan MB. Govindarajan S, et al. Among authors: lambrecht bn. Nat Commun. 2018 Dec 17;9(1):5340. doi: 10.1038/s41467-018-07758-x. Nat Commun. 2018. PMID: 30559399 Free PMC article.
Invariant natural killer T cells are natural regulators of murine spondylarthritis.
Jacques P, Venken K, Van Beneden K, Hammad H, Seeuws S, Drennan MB, Deforce D, Verbruggen G, Apostolaki M, Kollias G, Lambrecht BN, De Vos M, Elewaut D. Jacques P, et al. Among authors: lambrecht bn. Arthritis Rheum. 2010 Apr;62(4):988-99. doi: 10.1002/art.27324. Arthritis Rheum. 2010. PMID: 20131252 Free article.
Disruption of the SapM locus in Mycobacterium bovis BCG improves its protective efficacy as a vaccine against M. tuberculosis.
Festjens N, Bogaert P, Batni A, Houthuys E, Plets E, Vanderschaeghe D, Laukens B, Asselbergh B, Parthoens E, De Rycke R, Willart MA, Jacques P, Elewaut D, Brouckaert P, Lambrecht BN, Huygen K, Callewaert N. Festjens N, et al. Among authors: lambrecht bn. EMBO Mol Med. 2011 Apr;3(4):222-34. doi: 10.1002/emmm.201000125. Epub 2011 Feb 16. EMBO Mol Med. 2011. PMID: 21328541 Free PMC article.
The ubiquitin-editing protein A20 prevents dendritic cell activation, recognition of apoptotic cells, and systemic autoimmunity.
Kool M, van Loo G, Waelput W, De Prijck S, Muskens F, Sze M, van Praet J, Branco-Madeira F, Janssens S, Reizis B, Elewaut D, Beyaert R, Hammad H, Lambrecht BN. Kool M, et al. Among authors: lambrecht bn. Immunity. 2011 Jul 22;35(1):82-96. doi: 10.1016/j.immuni.2011.05.013. Epub 2011 Jun 30. Immunity. 2011. PMID: 21723156 Free article.
A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis.
Matmati M, Jacques P, Maelfait J, Verheugen E, Kool M, Sze M, Geboes L, Louagie E, Mc Guire C, Vereecke L, Chu Y, Boon L, Staelens S, Matthys P, Lambrecht BN, Schmidt-Supprian M, Pasparakis M, Elewaut D, Beyaert R, van Loo G. Matmati M, et al. Among authors: lambrecht bn. Nat Genet. 2011 Aug 14;43(9):908-12. doi: 10.1038/ng.874. Nat Genet. 2011. PMID: 21841782
The UPR and lung disease.
Osorio F, Lambrecht B, Janssens S. Osorio F, et al. Semin Immunopathol. 2013 May;35(3):293-306. doi: 10.1007/s00281-013-0368-6. Epub 2013 Mar 28. Semin Immunopathol. 2013. PMID: 23536202 Review.
455 results