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Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis.
Campa CC, Silva RL, Margaria JP, Pirali T, Mattos MS, Kraemer LR, Reis DC, Grosa G, Copperi F, Dalmarco EM, Lima-Júnior RCP, Aprile S, Sala V, Dal Bello F, Prado DS, Alves-Filho JC, Medana C, Cassali GD, Tron GC, Teixeira MM, Ciraolo E, Russo RC, Hirsch E. Campa CC, et al. Among authors: prado ds. Nat Commun. 2018 Dec 12;9(1):5232. doi: 10.1038/s41467-018-07698-6. Nat Commun. 2018. PMID: 30542075 Free PMC article.
NLRP3 Inflammasome Mediates Aldosterone-Induced Vascular Damage.
Bruder-Nascimento T, Ferreira NS, Zanotto CZ, Ramalho F, Pequeno IO, Olivon VC, Neves KB, Alves-Lopes R, Campos E, Silva CA, Fazan R, Carlos D, Mestriner FL, Prado D, Pereira FV, Braga T, Luiz JP, Cau SB, Elias PC, Moreira AC, Câmara NO, Zamboni DS, Alves-Filho JC, Tostes RC. Bruder-Nascimento T, et al. Among authors: prado d. Circulation. 2016 Dec 6;134(23):1866-1880. doi: 10.1161/CIRCULATIONAHA.116.024369. Epub 2016 Nov 1. Circulation. 2016. PMID: 27803035 Free article.
MEK5/ERK5 signaling mediates IL-4-induced M2 macrophage differentiation through regulation of c-Myc expression.
Luiz JPM, Toller-Kawahisa JE, Viacava PR, Nascimento DC, Pereira PT, Saraiva AL, Prado DS, LeBert M, Giurisato E, Tournier C, Cunha TM, Cunha FQ, Quesniaux V, Ryffel B, Alves-Filho JC. Luiz JPM, et al. Among authors: prado ds. J Leukoc Biol. 2020 Oct;108(4):1215-1223. doi: 10.1002/JLB.1MA0520-016R. Epub 2020 Aug 3. J Leukoc Biol. 2020. PMID: 32745297
Pyruvate kinase M2 mediates IL-17 signaling in keratinocytes driving psoriatic skin inflammation.
Veras FP, Publio GA, Melo BM, Prado DS, Norbiato T, Cecilio NT, Hiroki C, Damasceno LEA, Jung R, Toller-Kawahisa JE, Martins TV, Assunção SF, Lima D, Alves MG, Vieira GV, Tavares LA, Alves-Rezende ALR, Karbach SH, Nakaya HI, Cunha TM, Souza CS, Cunha FQ, Sales KU, Waisman A, Alves-Filho JC. Veras FP, et al. Among authors: prado ds. Cell Rep. 2022 Dec 27;41(13):111897. doi: 10.1016/j.celrep.2022.111897. Cell Rep. 2022. PMID: 36577385 Free article.
Paediatric sepsis survivors are resistant to sepsis-induced long-term immune dysfunction.
Colón DF, Wanderley CW, Turato WM, Borges VF, Franchin M, Castanheira FVS, Nascimento D, Prado D, Haruo Fernandes de Lima M, Volpon LC, Kavaguti SK, Carlotti AP, Carmona F, Franklin BS, Cunha TM, Alves-Filho JC, Cunha FQ. Colón DF, et al. Br J Pharmacol. 2024 Apr;181(8):1308-1323. doi: 10.1111/bph.16286. Epub 2024 Jan 11. Br J Pharmacol. 2024. PMID: 37990806
Citronellol reduces orofacial nociceptive behaviour in mice - evidence of involvement of retrosplenial cortex and periaqueductal grey areas.
Brito RG, Santos PL, Prado DS, Santana MT, Araújo AA, Bonjardim LR, Santos MR, de Lucca Júnior W, Oliveira AP, Quintans-Júnior LJ. Brito RG, et al. Among authors: prado ds. Basic Clin Pharmacol Toxicol. 2013 Apr;112(4):215-21. doi: 10.1111/bcpt.12018. Epub 2012 Nov 7. Basic Clin Pharmacol Toxicol. 2013. PMID: 23035741 Free article.
28 results