Søndergaard MT - Search Results

1

Ca²⁺-dependent calmodulin binding to cardiac ryanodine receptor (RyR2) calmodulin-binding domains.

Brohus M, Søndergaard MT, Wayne Chen SR, van Petegem F, Overgaard MT. Brohus M, et al. Among authors: sondergaard mt. Biochem J. 2019 Jan 18;476(2):193-209. doi: 10.1042/BCJ20180545. Biochem J. 2019. PMID: 30530841 Free PMC article.

2

Mutations in calmodulin cause ventricular tachycardia and sudden cardiac death.

Nyegaard M, Overgaard MT, Søndergaard MT, Vranas M, Behr ER, Hildebrandt LL, Lund J, Hedley PL, Camm AJ, Wettrell G, Fosdal I, Christiansen M, Børglum AD. Nyegaard M, et al. Among authors: sondergaard mt. Am J Hum Genet. 2012 Oct 5;91(4):703-12. doi: 10.1016/j.ajhg.2012.08.015. Am J Hum Genet. 2012. PMID: 23040497 Free PMC article.

3

Expression of Fap amyloids in Pseudomonas aeruginosa, P. fluorescens, and P. putida results in aggregation and increased biofilm formation.

Dueholm MS, Søndergaard MT, Nilsson M, Christiansen G, Stensballe A, Overgaard MT, Givskov M, Tolker-Nielsen T, Otzen DE, Nielsen PH. Dueholm MS, et al. Among authors: sondergaard mt. Microbiologyopen. 2013 Jun;2(3):365-82. doi: 10.1002/mbo3.81. Epub 2013 Mar 18. Microbiologyopen. 2013. PMID: 23504942 Free PMC article.

4

Calmodulin in a heartbeat.

Sorensen AB, Søndergaard MT, Overgaard MT. Sorensen AB, et al. Among authors: sondergaard mt. FEBS J. 2013 Nov;280(21):5511-32. doi: 10.1111/febs.12337. Epub 2013 Jun 18. FEBS J. 2013. PMID: 23663249 Free article. Review.

5

Heparin-binding mechanism of the IGF2/IGF-binding protein 2 complex.

Lund J, Søndergaard MT, Conover CA, Overgaard MT. Lund J, et al. Among authors: sondergaard mt. J Mol Endocrinol. 2014 Jun;52(3):345-55. doi: 10.1530/JME-13-0184. Epub 2014 Mar 6. J Mol Endocrinol. 2014. PMID: 24604839

6

Calmodulin mutations causing catecholaminergic polymorphic ventricular tachycardia confer opposing functional and biophysical molecular changes.

Søndergaard MT, Sorensen AB, Skov LL, Kjaer-Sorensen K, Bauer MC, Nyegaard M, Linse S, Oxvig C, Overgaard MT. Søndergaard MT, et al. FEBS J. 2015 Feb;282(4):803-16. doi: 10.1111/febs.13184. Epub 2015 Jan 14. FEBS J. 2015. PMID: 25557436 Free article.

7

Arrhythmogenic Calmodulin Mutations Affect the Activation and Termination of Cardiac Ryanodine Receptor-mediated Ca2+ Release.

Søndergaard MT, Tian X, Liu Y, Wang R, Chazin WJ, Chen SR, Overgaard MT. Søndergaard MT, et al. J Biol Chem. 2015 Oct 23;290(43):26151-62. doi: 10.1074/jbc.M115.676627. Epub 2015 Aug 26. J Biol Chem. 2015. PMID: 26309258 Free PMC article.

8

The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+ Binding but Not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor.

Søndergaard MT, Liu Y, Larsen KT, Nani A, Tian X, Holt C, Wang R, Wimmer R, Van Petegem F, Fill M, Chen SR, Overgaard MT. Søndergaard MT, et al. J Biol Chem. 2017 Jan 27;292(4):1385-1395. doi: 10.1074/jbc.M116.766253. Epub 2016 Dec 7. J Biol Chem. 2017. PMID: 27927985 Free PMC article.

9

Diminished inhibition and facilitated activation of RyR2-mediated Ca²⁺ release is a common defect of arrhythmogenic calmodulin mutations.

Søndergaard MT, Liu Y, Brohus M, Guo W, Nani A, Carvajal C, Fill M, Overgaard MT, Chen SRW. Søndergaard MT, et al. FEBS J. 2019 Nov;286(22):4554-4578. doi: 10.1111/febs.14969. Epub 2019 Jul 12. FEBS J. 2019. PMID: 31230402 Free article.

10

Role of cardiac ryanodine receptor calmodulin-binding domains in mediating the action of arrhythmogenic calmodulin N-domain mutation N54I.

Søndergaard MT, Liu Y, Guo W, Wei J, Wang R, Brohus M, Overgaard MT, Chen SRW. Søndergaard MT, et al. FEBS J. 2020 Jun;287(11):2256-2280. doi: 10.1111/febs.15147. Epub 2019 Dec 18. FEBS J. 2020. PMID: 31763755 Free article.

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