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Triazolopyrimidine and triazolopyridine scaffolds as TDP2 inhibitors.
Ribeiro CJA, Kankanala J, Xie J, Williams J, Aihara H, Wang Z. Ribeiro CJA, et al. Among authors: kankanala j. Bioorg Med Chem Lett. 2019 Jan 15;29(2):257-261. doi: 10.1016/j.bmcl.2018.11.044. Epub 2018 Nov 22. Bioorg Med Chem Lett. 2019. PMID: 30522956 Free PMC article.
Novel deazaflavin tyrosyl-DNA phosphodiesterase 2 (TDP2) inhibitors.
Kiselev E, Ravji A, Kankanala J, Xie J, Wang Z, Pommier Y. Kiselev E, et al. Among authors: kankanala j. DNA Repair (Amst). 2020 Jan;85:102747. doi: 10.1016/j.dnarep.2019.102747. Epub 2019 Nov 6. DNA Repair (Amst). 2020. PMID: 31775111 Free PMC article.
Design, synthesis, biochemical, and antiviral evaluations of C6 benzyl and C6 biarylmethyl substituted 2-hydroxylisoquinoline-1,3-diones: dual inhibition against HIV reverse transcriptase-associated RNase H and polymerase with antiviral activities.
Vernekar SK, Liu Z, Nagy E, Miller L, Kirby KA, Wilson DJ, Kankanala J, Sarafianos SG, Parniak MA, Wang Z. Vernekar SK, et al. Among authors: kankanala j. J Med Chem. 2015 Jan 22;58(2):651-64. doi: 10.1021/jm501132s. Epub 2014 Dec 30. J Med Chem. 2015. PMID: 25522204 Free PMC article.
30 results