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Tumor-draining lymph nodes are pivotal in PD-1/PD-L1 checkpoint therapy.
Fransen MF, Schoonderwoerd M, Knopf P, Camps MG, Hawinkels LJ, Kneilling M, van Hall T, Ossendorp F. Fransen MF, et al. Among authors: hawinkels lj. JCI Insight. 2018 Dec 6;3(23):e124507. doi: 10.1172/jci.insight.124507. JCI Insight. 2018. PMID: 30518694 Free PMC article.
Intestinal BMP-9 locally upregulates FGF19 and is down-regulated in obese patients with diabetes.
Drexler S, Cai C, Hartmann AL, Moch D, Gaitantzi H, Ney T, Kraemer M, Chu Y, Zheng Y, Rahbari M, Treffs A, Reiser A, Lenoir B, Valous NA, Jäger D, Birgin E, Sawant TA, Li Q, Xu K, Dong L, Otto M, Itzel T, Teufel A, Gretz N, Hawinkels LJAC, Sánchez A, Herrera B, Schubert R, Moshage H, Reissfelder C, Ebert MPA, Rahbari NN, Breitkopf-Heinlein K. Drexler S, et al. Among authors: hawinkels ljac. Mol Cell Endocrinol. 2023 Jun 15;570:111934. doi: 10.1016/j.mce.2023.111934. Epub 2023 Apr 19. Mol Cell Endocrinol. 2023. PMID: 37085108 Free article.
Endoglin Expression on Cancer-Associated Fibroblasts Regulates Invasion and Stimulates Colorectal Cancer Metastasis.
Paauwe M, Schoonderwoerd MJA, Helderman RFCP, Harryvan TJ, Groenewoud A, van Pelt GW, Bor R, Hemmer DM, Versteeg HH, Snaar-Jagalska BE, Theuer CP, Hardwick JCH, Sier CFM, Ten Dijke P, Hawinkels LJAC. Paauwe M, et al. Clin Cancer Res. 2018 Dec 15;24(24):6331-6344. doi: 10.1158/1078-0432.CCR-18-0329. Epub 2018 Jun 26. Clin Cancer Res. 2018. PMID: 29945992
Mesenchymal Stromal Cell-Derived Exosomes Contribute to Epithelial Regeneration in Experimental Inflammatory Bowel Disease.
Barnhoorn MC, Plug L, Jonge ESMM, Molenkamp D, Bos E, Schoonderwoerd MJA, Corver WE, van der Meulen-de Jong AE, Verspaget HW, Hawinkels LJAC. Barnhoorn MC, et al. Cell Mol Gastroenterol Hepatol. 2020;9(4):715-717.e8. doi: 10.1016/j.jcmgh.2020.01.007. Epub 2020 Jan 23. Cell Mol Gastroenterol Hepatol. 2020. PMID: 31982571 Free PMC article. No abstract available.
Endoglin: Beyond the Endothelium.
Schoonderwoerd MJA, Goumans MTH, Hawinkels LJAC. Schoonderwoerd MJA, et al. Biomolecules. 2020 Feb 12;10(2):289. doi: 10.3390/biom10020289. Biomolecules. 2020. PMID: 32059544 Free PMC article. Review.
Targeting Endoglin-Expressing Regulatory T Cells in the Tumor Microenvironment Enhances the Effect of PD1 Checkpoint Inhibitor Immunotherapy.
Schoonderwoerd MJA, Koops MFM, Angela RA, Koolmoes B, Toitou M, Paauwe M, Barnhoorn MC, Liu Y, Sier CFM, Hardwick JCH, Nixon AB, Theuer CP, Fransen MF, Hawinkels LJAC. Schoonderwoerd MJA, et al. Clin Cancer Res. 2020 Jul 15;26(14):3831-3842. doi: 10.1158/1078-0432.CCR-19-2889. Epub 2020 Apr 24. Clin Cancer Res. 2020. PMID: 32332012
Adenoviral vaccines promote protective tissue-resident memory T cell populations against cancer.
van der Gracht ET, Schoonderwoerd MJ, van Duikeren S, Yilmaz AN, Behr FM, Colston JM, Lee LN, Yagita H, van Gisbergen KP, Hawinkels LJ, Koning F, Klenerman P, Arens R. van der Gracht ET, et al. Among authors: hawinkels lj. J Immunother Cancer. 2020 Dec;8(2):e001133. doi: 10.1136/jitc-2020-001133. J Immunother Cancer. 2020. PMID: 33293355 Free PMC article.
92 results