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SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells.
Sociali G, Grozio A, Caffa I, Schuster S, Becherini P, Damonte P, Sturla L, Fresia C, Passalacqua M, Mazzola F, Raffaelli N, Garten A, Kiess W, Cea M, Nencioni A, Bruzzone S. Sociali G, et al. Among authors: cea m. FASEB J. 2019 Mar;33(3):3704-3717. doi: 10.1096/fj.201800321R. Epub 2018 Dec 4. FASEB J. 2019. PMID: 30514106 Free PMC article.
., Becherini, P., Damonte, P., Sturla, L., Fresia, C., Passalacqua, M., Mazzola, F., Raffaelli, N., Garten, A., Kiess, W., Cea, M., Nencioni, A., Bruzzone, S. ...
., Becherini, P., Damonte, P., Sturla, L., Fresia, C., Passalacqua, M., Mazzola, F., Raffaelli, N., Garten, A., Kiess, W., Cea …
Targeting the immune microenvironment in Waldenström macroglobulinemia via halting the CD40/CD40-ligand axis.
Sacco A, Desantis V, Celay J, Giustini V, Rigali F, Savino FD, Cea M, Soncini D, Cagnetta A, Solimando AG, D'Aliberti D, Spinelli S, Ramazzotti D, Almici C, Todoerti K, Neri A, Anastasia A, Tucci A, Motta M, Chiarini M, Kawano Y, Martinez-Climent JA, Piazza R, Roccaro AM. Sacco A, et al. Among authors: cea m. Blood. 2023 May 25;141(21):2615-2628. doi: 10.1182/blood.2022019240. Blood. 2023. PMID: 36735903 Free article.
Catastrophic NAD+ depletion in activated T lymphocytes through Nampt inhibition reduces demyelination and disability in EAE.
Bruzzone S, Fruscione F, Morando S, Ferrando T, Poggi A, Garuti A, D'Urso A, Selmo M, Benvenuto F, Cea M, Zoppoli G, Moran E, Soncini D, Ballestrero A, Sordat B, Patrone F, Mostoslavsky R, Uccelli A, Nencioni A. Bruzzone S, et al. Among authors: cea m. PLoS One. 2009 Nov 19;4(11):e7897. doi: 10.1371/journal.pone.0007897. PLoS One. 2009. PMID: 19936064 Free PMC article.
Ras-induced resistance to lapatinib is overcome by MEK inhibition.
Zoppoli G, Moran E, Soncini D, Cea M, Garuti A, Rocco I, Cirmena G, Grillo V, Bagnasco L, Icardi G, Ansaldi F, Parodi S, Patrone F, Ballestrero A, Nencioni A. Zoppoli G, et al. Among authors: cea m. Curr Cancer Drug Targets. 2010 Mar;10(2):168-75. doi: 10.2174/156800910791054211. Curr Cancer Drug Targets. 2010. PMID: 20088787
Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells.
Zoppoli G, Cea M, Soncini D, Fruscione F, Rudner J, Moran E, Caffa I, Bedognetti D, Motta G, Ghio R, Ferrando F, Ballestrero A, Parodi S, Belka C, Patrone F, Bruzzone S, Nencioni A. Zoppoli G, et al. Among authors: cea m. Exp Hematol. 2010 Nov;38(11):979-88. doi: 10.1016/j.exphem.2010.07.013. Epub 2010 Aug 7. Exp Hematol. 2010. PMID: 20696207 Free article.
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells.
Cea M, Soncini D, Fruscione F, Raffaghello L, Garuti A, Emionite L, Moran E, Magnone M, Zoppoli G, Reverberi D, Caffa I, Salis A, Cagnetta A, Bergamaschi M, Casciaro S, Pierri I, Damonte G, Ansaldi F, Gobbi M, Pistoia V, Ballestrero A, Patrone F, Bruzzone S, Nencioni A. Cea M, et al. PLoS One. 2011;6(7):e22739. doi: 10.1371/journal.pone.0022739. Epub 2011 Jul 27. PLoS One. 2011. PMID: 21818379 Free PMC article.
151 results