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EZH2, HIF-1, and Their Inhibitors: An Overview on Pediatric Cancers.
Papale M, Ferretti E, Battaglia G, Bellavia D, Mai A, Tafani M. Papale M, et al. Among authors: ferretti e. Front Pediatr. 2018 Nov 19;6:328. doi: 10.3389/fped.2018.00328. eCollection 2018. Front Pediatr. 2018. PMID: 30510924 Free PMC article. Review.
PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress.
Mazzà D, Infante P, Colicchia V, Greco A, Alfonsi R, Siler M, Antonucci L, Po A, De Smaele E, Ferretti E, Capalbo C, Bellavia D, Canettieri G, Giannini G, Screpanti I, Gulino A, Di Marcotullio L. Mazzà D, et al. Among authors: ferretti e. Cell Death Differ. 2013 Dec;20(12):1688-97. doi: 10.1038/cdd.2013.120. Epub 2013 Sep 6. Cell Death Differ. 2013. PMID: 24013724 Free PMC article.
Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells.
Valente S, Liu Y, Schnekenburger M, Zwergel C, Cosconati S, Gros C, Tardugno M, Labella D, Florean C, Minden S, Hashimoto H, Chang Y, Zhang X, Kirsch G, Novellino E, Arimondo PB, Miele E, Ferretti E, Gulino A, Diederich M, Cheng X, Mai A. Valente S, et al. Among authors: ferretti e. J Med Chem. 2014 Feb 13;57(3):701-13. doi: 10.1021/jm4012627. Epub 2014 Jan 15. J Med Chem. 2014. PMID: 24387159 Free PMC article.
Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma.
Coni S, Mancuso AB, Di Magno L, Sdruscia G, Manni S, Serrao SM, Rotili D, Spiombi E, Bufalieri F, Petroni M, Kusio-Kobialka M, De Smaele E, Ferretti E, Capalbo C, Mai A, Niewiadomski P, Screpanti I, Di Marcotullio L, Canettieri G. Coni S, et al. Among authors: ferretti e. Sci Rep. 2017 Mar 9;7:44079. doi: 10.1038/srep44079. Sci Rep. 2017. PMID: 28276480 Free PMC article.
The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells.
Miele E, Valente S, Alfano V, Silvano M, Mellini P, Borovika D, Marrocco B, Po A, Besharat ZM, Catanzaro G, Battaglia G, Abballe L, Zwergel C, Stazi G, Milite C, Castellano S, Tafani M, Trapencieris P, Mai A, Ferretti E. Miele E, et al. Among authors: ferretti e. Oncotarget. 2017 Aug 2;8(40):68557-68570. doi: 10.18632/oncotarget.19782. eCollection 2017 Sep 15. Oncotarget. 2017. PMID: 28978137 Free PMC article.
Loss of miR-107, miR-181c and miR-29a-3p Promote Activation of Notch2 Signaling in Pediatric High-Grade Gliomas (pHGGs).
Catanzaro G, Sabato C, Russo M, Rosa A, Abballe L, Besharat ZM, Po A, Miele E, Bellavia D, Chiacchiarini M, Gessi M, Peruzzi G, Napolitano M, Antonelli M, Mastronuzzi A, Giangaspero F, Locatelli F, Screpanti I, Vacca A, Ferretti E. Catanzaro G, et al. Among authors: ferretti e. Int J Mol Sci. 2017 Dec 17;18(12):2742. doi: 10.3390/ijms18122742. Int J Mol Sci. 2017. PMID: 29258209 Free PMC article.
Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells.
Mellini P, Marrocco B, Borovika D, Polletta L, Carnevale I, Saladini S, Stazi G, Zwergel C, Trapencieris P, Ferretti E, Tafani M, Valente S, Mai A. Mellini P, et al. Among authors: ferretti e. Philos Trans R Soc Lond B Biol Sci. 2018 Jun 5;373(1748):20170150. doi: 10.1098/rstb.2017.0150. Philos Trans R Soc Lond B Biol Sci. 2018. PMID: 29685965 Free PMC article.
Correction to 'Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells'.
Mellini P, Marrocco B, Borovika D, Polletta L, Carnevale I, Saladini S, Stazi G, Zwergel C, Trapencieris P, Ferretti E, Tafani M, Valente S, Mai A. Mellini P, et al. Among authors: ferretti e. Philos Trans R Soc Lond B Biol Sci. 2018 Sep 19;373(1755):20180305. doi: 10.1098/rstb.2018.0305. Philos Trans R Soc Lond B Biol Sci. 2018. PMID: 30061471 Free PMC article. No abstract available.
423 results