Sayers TJ - Search Results

1

Sensitization of renal carcinoma cells to TRAIL-induced apoptosis by rocaglamide and analogs.

Nalli AD, Brown LE, Thomas CL, Sayers TJ, Porco JA Jr, Henrich CJ. Nalli AD, et al. Among authors: sayers tj. Sci Rep. 2018 Nov 30;8(1):17519. doi: 10.1038/s41598-018-35908-0. Sci Rep. 2018. PMID: 30504817 Free PMC article.

2

A cell-based high-throughput screen to identify synergistic TRAIL sensitizers.

Booth NL, Sayers TJ, Brooks AD, Thomas CL, Jacobsen K, Goncharova EI, McMahon JB, Henrich CJ. Booth NL, et al. Among authors: sayers tj. Cancer Immunol Immunother. 2009 Aug;58(8):1229-44. doi: 10.1007/s00262-008-0637-8. Epub 2008 Dec 17. Cancer Immunol Immunother. 2009. PMID: 19089423 Free PMC article.

3

Effects of cucurbitacins on cell morphology are associated with sensitization of renal carcinoma cells to TRAIL-induced apoptosis.

Henrich CJ, Thomas CL, Brooks AD, Booth NL, Lowery EM, Pompei RJ, McMahon JB, Sayers TJ. Henrich CJ, et al. Among authors: sayers tj. Apoptosis. 2012 Jan;17(1):79-89. doi: 10.1007/s10495-011-0652-7. Apoptosis. 2012. PMID: 21928090 Free PMC article.

4

17β-Hydroxywithanolides as Sensitizers of Renal Carcinoma Cells to Tumor Necrosis Factor-α Related Apoptosis Inducing Ligand (TRAIL) Mediated Apoptosis: Structure-Activity Relationships.

Xu YM, Brooks AD, Wijeratne EM, Henrich CJ, Tewary P, Sayers TJ, Gunatilaka AA. Xu YM, et al. Among authors: sayers tj. J Med Chem. 2017 Apr 13;60(7):3039-3051. doi: 10.1021/acs.jmedchem.7b00069. Epub 2017 Mar 21. J Med Chem. 2017. PMID: 28257574 Free PMC article.

5

Withanolide E sensitizes renal carcinoma cells to TRAIL-induced apoptosis by increasing cFLIP degradation.

Henrich CJ, Brooks AD, Erickson KL, Thomas CL, Bokesch HR, Tewary P, Thompson CR, Pompei RJ, Gustafson KR, McMahon JB, Sayers TJ. Henrich CJ, et al. Among authors: sayers tj. Cell Death Dis. 2015 Feb 26;6(2):e1666. doi: 10.1038/cddis.2015.38. Cell Death Dis. 2015. PMID: 25719250 Free PMC article.

6

Clerodane diterpenes from Casearia arguta that act as synergistic TRAIL sensitizers.

Whitson EL, Thomas CL, Henrich CJ, Sayers TJ, McMahon JB, McKee TC. Whitson EL, et al. Among authors: sayers tj. J Nat Prod. 2010 Dec 27;73(12):2013-8. doi: 10.1021/np1004455. Epub 2010 Nov 10. J Nat Prod. 2010. PMID: 21067210 Free PMC article.

7

Synergistic TRAIL sensitizers from Barleria alluaudii and Diospyros maritima.

Whitson EL, Sun H, Thomas CL, Henrich CJ, Sayers TJ, McMahon JB, Griesinger C, McKee TC. Whitson EL, et al. Among authors: sayers tj. J Nat Prod. 2012 Mar 23;75(3):394-9. doi: 10.1021/np200805z. Epub 2012 Feb 7. J Nat Prod. 2012. PMID: 22313254 Free PMC article.

8

Small-Molecule Natural Product Physachenolide C Potentiates Immunotherapy Efficacy by Targeting BET Proteins.

Tewary P, Brooks AD, Xu YM, Wijeratne EMK, Babyak AL, Back TC, Chari R, Evans CN, Henrich CJ, Meyer TJ, Edmondson EF, de Aquino MTP, Kanagasabai T, Shanker A, Gunatilaka AAL, Sayers TJ. Tewary P, et al. Among authors: sayers tj. Cancer Res. 2021 Jun 15;81(12):3374-3386. doi: 10.1158/0008-5472.CAN-20-2634. Epub 2021 Apr 9. Cancer Res. 2021. PMID: 33837043 Free PMC article.

9

Reduction of the antiapoptotic protein cFLIP enhances the susceptibility of human renal cancer cells to TRAIL apoptosis.

Brooks AD, Sayers TJ. Brooks AD, et al. Among authors: sayers tj. Cancer Immunol Immunother. 2005 May;54(5):499-505. doi: 10.1007/s00262-004-0595-8. Epub 2004 Dec 22. Cancer Immunol Immunother. 2005. PMID: 15614529 Free PMC article.

10

The proteasome inhibitor bortezomib (Velcade) sensitizes some human tumor cells to Apo2L/TRAIL-mediated apoptosis.

Brooks AD, Ramirez T, Toh U, Onksen J, Elliott PJ, Murphy WJ, Sayers TJ. Brooks AD, et al. Among authors: sayers tj. Ann N Y Acad Sci. 2005 Nov;1059:160-7. doi: 10.1196/annals.1339.042. Ann N Y Acad Sci. 2005. PMID: 16382051

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