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PPARβ/δ-agonist GW0742 ameliorates dysfunction in fatty acid oxidation in PSEN1ΔE9 astrocytes.
Konttinen H, Gureviciene I, Oksanen M, Grubman A, Loppi S, Huuskonen MT, Korhonen P, Lampinen R, Keuters M, Belaya I, Tanila H, Kanninen KM, Goldsteins G, Landreth G, Koistinaho J, Malm T. Konttinen H, et al. Among authors: goldsteins g. Glia. 2019 Jan;67(1):146-159. doi: 10.1002/glia.23534. Epub 2018 Nov 19. Glia. 2019. PMID: 30453390 Free PMC article.
Nuclear factor erythroid 2-related factor 2 protects against beta amyloid.
Kanninen K, Malm TM, Jyrkkänen HK, Goldsteins G, Keksa-Goldsteine V, Tanila H, Yamamoto M, Ylä-Herttuala S, Levonen AL, Koistinaho J. Kanninen K, et al. Among authors: goldsteins g. Mol Cell Neurosci. 2008 Nov;39(3):302-13. doi: 10.1016/j.mcn.2008.07.010. Epub 2008 Jul 29. Mol Cell Neurosci. 2008. PMID: 18706502
Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytes.
Liddell JR, Lehtonen S, Duncan C, Keksa-Goldsteine V, Levonen AL, Goldsteins G, Malm T, White AR, Koistinaho J, Kanninen KM. Liddell JR, et al. Among authors: goldsteins g. J Neuroinflammation. 2016 Feb 26;13:49. doi: 10.1186/s12974-016-0515-9. J Neuroinflammation. 2016. PMID: 26920699 Free PMC article.
Bexarotene targets autophagy and is protective against thromboembolic stroke in aged mice with tauopathy.
Huuskonen MT, Loppi S, Dhungana H, Keksa-Goldsteine V, Lemarchant S, Korhonen P, Wojciechowski S, Pollari E, Valonen P, Koponen J, Takashima A, Landreth G, Goldsteins G, Malm T, Koistinaho J, Kanninen KM. Huuskonen MT, et al. Among authors: goldsteins g. Sci Rep. 2016 Sep 14;6:33176. doi: 10.1038/srep33176. Sci Rep. 2016. PMID: 27624652 Free PMC article.
Neuron-astrocyte transmitophagy is altered in Alzheimer's disease.
Lampinen R, Belaya I, Saveleva L, Liddell JR, Rait D, Huuskonen MT, Giniatullina R, Sorvari A, Soppela L, Mikhailov N, Boccuni I, Giniatullin R, Cruz-Haces M, Konovalova J, Koskuvi M, Domanskyi A, Hämäläinen RH, Goldsteins G, Koistinaho J, Malm T, Chew S, Rilla K, White AR, Marsh-Armstrong N, Kanninen KM. Lampinen R, et al. Among authors: goldsteins g. Neurobiol Dis. 2022 Aug;170:105753. doi: 10.1016/j.nbd.2022.105753. Epub 2022 May 13. Neurobiol Dis. 2022. PMID: 35569719 Free article.
54 results