Rada-Iglesias A - Search Results

1

Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations.

Irmak D, Fatima A, Gutiérrez-Garcia R, Rinschen MM, Wagle P, Altmüller J, Arrigoni L, Hummel B, Klein C, Frese CK, Sawarkar R, Rada-Iglesias A, Vilchez D. Irmak D, et al. Hum Mol Genet. 2018 Dec 1;27(23):4117-4134. doi: 10.1093/hmg/ddy304. Hum Mol Genet. 2018. PMID: 30452683

2

GARLIC: a bioinformatic toolkit for aetiologically connecting diseases and cell type-specific regulatory maps.

Nikolic M, Papantonis A, Rada-Iglesias A. Nikolic M, et al. Hum Mol Genet. 2017 Feb 15;26(4):742-752. doi: 10.1093/hmg/ddw423. Hum Mol Genet. 2017. PMID: 28007912 Free PMC article.

3

Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip ± cleft palate and cleft palate only.

Ludwig KU, Böhmer AC, Bowes J, Nikolic M, Ishorst N, Wyatt N, Hammond NL, Gölz L, Thieme F, Barth S, Schuenke H, Klamt J, Spielmann M, Aldhorae K, Rojas-Martinez A, Nöthen MM, Rada-Iglesias A, Dixon MJ, Knapp M, Mangold E. Ludwig KU, et al. Hum Mol Genet. 2017 Feb 15;26(4):829-842. doi: 10.1093/hmg/ddx012. Hum Mol Genet. 2017. PMID: 28087736 Free PMC article.

4

PRC2 Facilitates the Regulatory Topology Required for Poised Enhancer Function during Pluripotent Stem Cell Differentiation.

Cruz-Molina S, Respuela P, Tebartz C, Kolovos P, Nikolic M, Fueyo R, van Ijcken WFJ, Grosveld F, Frommolt P, Bazzi H, Rada-Iglesias A. Cruz-Molina S, et al. Cell Stem Cell. 2017 May 4;20(5):689-705.e9. doi: 10.1016/j.stem.2017.02.004. Epub 2017 Mar 9. Cell Stem Cell. 2017. PMID: 28285903 Free article.

5

Chromatin Immunoprecipitation (ChIP) Protocol for Low-abundance Embryonic Samples.

Rehimi R, Bartusel M, Solinas F, Altmüller J, Rada-Iglesias A. Rehimi R, et al. J Vis Exp. 2017 Aug 29;(126):56186. doi: 10.3791/56186. J Vis Exp. 2017. PMID: 28872116 Free PMC article.

6

The ubiquitin-conjugating enzyme UBE2K determines neurogenic potential through histone H3 in human embryonic stem cells.

Fatima A, Irmak D, Noormohammadi A, Rinschen MM, Das A, Leidecker O, Schindler C, Sánchez-Gaya V, Wagle P, Pokrzywa W, Hoppe T, Rada-Iglesias A, Vilchez D. Fatima A, et al. Commun Biol. 2020 May 25;3(1):262. doi: 10.1038/s42003-020-0984-3. Commun Biol. 2020. PMID: 32451438 Free PMC article.

7

Niche stiffening compromises hair follicle stem cell potential during ageing by reducing bivalent promoter accessibility.

Koester J, Miroshnikova YA, Ghatak S, Chacón-Martínez CA, Morgner J, Li X, Atanassov I, Altmüller J, Birk DE, Koch M, Bloch W, Bartusel M, Niessen CM, Rada-Iglesias A, Wickström SA. Koester J, et al. Nat Cell Biol. 2021 Jul;23(7):771-781. doi: 10.1038/s41556-021-00705-x. Epub 2021 Jul 8. Nat Cell Biol. 2021. PMID: 34239060

8

Foxd3 Promotes Exit from Naive Pluripotency through Enhancer Decommissioning and Inhibits Germline Specification.

Respuela P, Nikolić M, Tan M, Frommolt P, Zhao Y, Wysocka J, Rada-Iglesias A. Respuela P, et al. Cell Stem Cell. 2016 Jan 7;18(1):118-33. doi: 10.1016/j.stem.2015.09.010. Cell Stem Cell. 2016. PMID: 26748758 Free PMC article.

9

Ready, Set…Poised!: Polycomb target genes are bound by poised RNA polymerase II throughout differentiation.

Rada-Iglesias A. Rada-Iglesias A. Mol Syst Biol. 2017 Oct 23;13(10):950. doi: 10.15252/msb.20177968. Mol Syst Biol. 2017. PMID: 29061670 Free PMC article.

10

Pioneering of Enhancer Landscapes during Pluripotent State Transitions.

Rada-Iglesias A. Rada-Iglesias A. Cell Stem Cell. 2018 Aug 2;23(2):149-151. doi: 10.1016/j.stem.2018.07.012. Cell Stem Cell. 2018. PMID: 30075122 Free article.

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