Otsuguro S - Search Results

1

Repurposing existing drugs: identification of irreversible IMPDH inhibitors by high-throughput screening.

Sarwono AEY, Mitsuhashi S, Kabir MHB, Shigetomi K, Okada T, Ohsaka F, Otsuguro S, Maenaka K, Igarashi M, Kato K, Ubukata M. Sarwono AEY, et al. Among authors: otsuguro s. J Enzyme Inhib Med Chem. 2019 Dec;34(1):171-178. doi: 10.1080/14756366.2018.1540474. J Enzyme Inhib Med Chem. 2019. PMID: 30451014 Free PMC article.

2

Application of Acoustic Ejection MS System to High-Throughput Screening for SARS-CoV-2 3CL Protease Inhibitors.

Hasegawa T, Imamura RM, Suzuki T, Hashiguchi T, Nomura T, Otsuguro S, Maenaka K, Sasaki M, Orba Y, Sawa H, Sato A, Okabe T, Nagano T, Kojima H. Hasegawa T, et al. Among authors: otsuguro s. Chem Pharm Bull (Tokyo). 2022 Mar 1;70(3):199-201. doi: 10.1248/cpb.c21-01003. Epub 2021 Dec 21. Chem Pharm Bull (Tokyo). 2022. PMID: 34937844 Free article.

3

Ribavirin-related compounds exert in vitro inhibitory effects toward rabies virus.

Anindita PD, Sasaki M, Okada K, Ito N, Sugiyama M, Saito-Tarashima N, Minakawa N, Shuto S, Otsuguro S, Ichikawa S, Matsuda A, Maenaka K, Orba Y, Sawa H. Anindita PD, et al. Among authors: otsuguro s. Antiviral Res. 2018 Jun;154:1-9. doi: 10.1016/j.antiviral.2018.03.011. Epub 2018 Mar 28. Antiviral Res. 2018. PMID: 29601893 Free article.

4

Suramin, screened from an approved drug library, inhibits HuR functions and attenuates malignant phenotype of oral cancer cells.

Kakuguchi W, Nomura T, Kitamura T, Otsuguro S, Matsushita K, Sakaitani M, Maenaka K, Tei K. Kakuguchi W, et al. Among authors: otsuguro s. Cancer Med. 2018 Dec;7(12):6269-6280. doi: 10.1002/cam4.1877. Epub 2018 Nov 18. Cancer Med. 2018. PMID: 30449075 Free PMC article.

5

Novel Notch signaling inhibitor NSI‑1 suppresses nuclear translocation of the Notch intracellular domain.

Shiraishi T, Sakaitani M, Otsuguro S, Maenaka K, Suzuki T, Nakaya T. Shiraishi T, et al. Among authors: otsuguro s. Int J Mol Med. 2019 Oct;44(4):1574-1584. doi: 10.3892/ijmm.2019.4280. Epub 2019 Jul 19. Int J Mol Med. 2019. PMID: 31364722

6

Structure, solubility, and permeability relationships in a diverse middle molecule library.

Miyachi H, Kanamitsu K, Ishii M, Watanabe E, Katsuyama A, Otsuguro S, Yakushiji F, Watanabe M, Matsui K, Sato Y, Shuto S, Tadokoro T, Kita S, Matsumaru T, Matsuda A, Hirose T, Iwatsuki M, Shigeta Y, Nagano T, Kojima H, Ichikawa S, Sunazuka T, Maenaka K. Miyachi H, et al. Among authors: otsuguro s. Bioorg Med Chem Lett. 2021 Apr 1;37:127847. doi: 10.1016/j.bmcl.2021.127847. Epub 2021 Feb 9. Bioorg Med Chem Lett. 2021. PMID: 33571648

7

High-Throughput Screening Assay Identifies Berberine and Mubritinib as Neuroprotection Drugs for Spinal Cord Injury via Blood-Spinal Cord Barrier Protection.

Suzuki Y, Nakagawa S, Endo T, Sotome A, Yuan R, Asano T, Otsuguro S, Maenaka K, Iwasaki N, Kadoya K. Suzuki Y, et al. Among authors: otsuguro s. Neurotherapeutics. 2022 Oct;19(6):1976-1991. doi: 10.1007/s13311-022-01310-y. Epub 2022 Sep 30. Neurotherapeutics. 2022. PMID: 36178590 Free PMC article.

8

Antitumor Effect of Sugar-Modified Cytosine Nucleosides on Growth of Adult T-Cell Leukemia Cells in Mice.

Maeda N, Matsuda A, Otsuguro S, Takahashi M, Fujii M, Maenaka K. Maeda N, et al. Among authors: otsuguro s. Vaccines (Basel). 2020 Nov 5;8(4):658. doi: 10.3390/vaccines8040658. Vaccines (Basel). 2020. PMID: 33167425 Free PMC article.

9

Divergent synthesis of kinase inhibitor derivatives, leading to discovery of selective Gck inhibitors.

Matsumaru T, Inai M, Ishigami K, Iwamatsu T, Maita H, Otsuguro S, Nomura T, Matsuda A, Ichikawa S, Sakaitani M, Shuto S, Maenaka K, Kan T. Matsumaru T, et al. Among authors: otsuguro s. Bioorg Med Chem Lett. 2017 May 15;27(10):2144-2147. doi: 10.1016/j.bmcl.2017.03.055. Epub 2017 Mar 23. Bioorg Med Chem Lett. 2017. PMID: 28385506 Free article.

10

Chemical Screening Identifies EUrd as a Novel Inhibitor Against Temozolomide-Resistant Glioblastoma-Initiating Cells.

Tsukamoto Y, Ohtsu N, Echizenya S, Otsuguro S, Ogura R, Natsumeda M, Isogawa M, Aoki H, Ichikawa S, Sakaitani M, Matsuda A, Maenaka K, Fujii Y, Kondo T. Tsukamoto Y, et al. Among authors: otsuguro s. Stem Cells. 2016 Aug;34(8):2016-25. doi: 10.1002/stem.2380. Epub 2016 May 17. Stem Cells. 2016. PMID: 27090194

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