Maenaka K - Search Results

1

Repurposing existing drugs: identification of irreversible IMPDH inhibitors by high-throughput screening.

Sarwono AEY, Mitsuhashi S, Kabir MHB, Shigetomi K, Okada T, Ohsaka F, Otsuguro S, Maenaka K, Igarashi M, Kato K, Ubukata M. Sarwono AEY, et al. Among authors: maenaka k. J Enzyme Inhib Med Chem. 2019 Dec;34(1):171-178. doi: 10.1080/14756366.2018.1540474. J Enzyme Inhib Med Chem. 2019. PMID: 30451014 Free PMC article.

2

The cell competition-based high-throughput screening identifies small compounds that promote the elimination of RasV12-transformed cells from epithelia.

Yamauchi H, Matsumaru T, Morita T, Ishikawa S, Maenaka K, Takigawa I, Semba K, Kon S, Fujita Y. Yamauchi H, et al. Among authors: maenaka k. Sci Rep. 2015 Oct 20;5:15336. doi: 10.1038/srep15336. Sci Rep. 2015. PMID: 26480891 Free PMC article.

3

Chemical Screening Identifies EUrd as a Novel Inhibitor Against Temozolomide-Resistant Glioblastoma-Initiating Cells.

Tsukamoto Y, Ohtsu N, Echizenya S, Otsuguro S, Ogura R, Natsumeda M, Isogawa M, Aoki H, Ichikawa S, Sakaitani M, Matsuda A, Maenaka K, Fujii Y, Kondo T. Tsukamoto Y, et al. Among authors: maenaka k. Stem Cells. 2016 Aug;34(8):2016-25. doi: 10.1002/stem.2380. Epub 2016 May 17. Stem Cells. 2016. PMID: 27090194

4

Divergent synthesis of kinase inhibitor derivatives, leading to discovery of selective Gck inhibitors.

Matsumaru T, Inai M, Ishigami K, Iwamatsu T, Maita H, Otsuguro S, Nomura T, Matsuda A, Ichikawa S, Sakaitani M, Shuto S, Maenaka K, Kan T. Matsumaru T, et al. Among authors: maenaka k. Bioorg Med Chem Lett. 2017 May 15;27(10):2144-2147. doi: 10.1016/j.bmcl.2017.03.055. Epub 2017 Mar 23. Bioorg Med Chem Lett. 2017. PMID: 28385506 Free article.

5

Structural and thermodynamic analyses reveal critical features of glycopeptide recognition by the human PILRα immune cell receptor.

Furukawa A, Kakita K, Yamada T, Ishizuka M, Sakamoto J, Hatori N, Maeda N, Ohsaka F, Saitoh T, Nomura T, Kuroki K, Nambu H, Arase H, Matsunaga S, Anada M, Ose T, Hashimoto S, Maenaka K. Furukawa A, et al. Among authors: maenaka k. J Biol Chem. 2017 Dec 22;292(51):21128-21136. doi: 10.1074/jbc.M117.799239. Epub 2017 Oct 18. J Biol Chem. 2017. PMID: 29046357 Free PMC article.

6

Ribavirin-related compounds exert in vitro inhibitory effects toward rabies virus.

Anindita PD, Sasaki M, Okada K, Ito N, Sugiyama M, Saito-Tarashima N, Minakawa N, Shuto S, Otsuguro S, Ichikawa S, Matsuda A, Maenaka K, Orba Y, Sawa H. Anindita PD, et al. Among authors: maenaka k. Antiviral Res. 2018 Jun;154:1-9. doi: 10.1016/j.antiviral.2018.03.011. Epub 2018 Mar 28. Antiviral Res. 2018. PMID: 29601893 Free article.

7

Suramin, screened from an approved drug library, inhibits HuR functions and attenuates malignant phenotype of oral cancer cells.

Kakuguchi W, Nomura T, Kitamura T, Otsuguro S, Matsushita K, Sakaitani M, Maenaka K, Tei K. Kakuguchi W, et al. Among authors: maenaka k. Cancer Med. 2018 Dec;7(12):6269-6280. doi: 10.1002/cam4.1877. Epub 2018 Nov 18. Cancer Med. 2018. PMID: 30449075 Free PMC article.

8

Novel Notch signaling inhibitor NSI‑1 suppresses nuclear translocation of the Notch intracellular domain.

Shiraishi T, Sakaitani M, Otsuguro S, Maenaka K, Suzuki T, Nakaya T. Shiraishi T, et al. Among authors: maenaka k. Int J Mol Med. 2019 Oct;44(4):1574-1584. doi: 10.3892/ijmm.2019.4280. Epub 2019 Jul 19. Int J Mol Med. 2019. PMID: 31364722

9

Antitumor Effect of Sugar-Modified Cytosine Nucleosides on Growth of Adult T-Cell Leukemia Cells in Mice.

Maeda N, Matsuda A, Otsuguro S, Takahashi M, Fujii M, Maenaka K. Maeda N, et al. Among authors: maenaka k. Vaccines (Basel). 2020 Nov 5;8(4):658. doi: 10.3390/vaccines8040658. Vaccines (Basel). 2020. PMID: 33167425 Free PMC article.

10

Structure, solubility, and permeability relationships in a diverse middle molecule library.

Miyachi H, Kanamitsu K, Ishii M, Watanabe E, Katsuyama A, Otsuguro S, Yakushiji F, Watanabe M, Matsui K, Sato Y, Shuto S, Tadokoro T, Kita S, Matsumaru T, Matsuda A, Hirose T, Iwatsuki M, Shigeta Y, Nagano T, Kojima H, Ichikawa S, Sunazuka T, Maenaka K. Miyachi H, et al. Among authors: maenaka k. Bioorg Med Chem Lett. 2021 Apr 1;37:127847. doi: 10.1016/j.bmcl.2021.127847. Epub 2021 Feb 9. Bioorg Med Chem Lett. 2021. PMID: 33571648

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