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Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus.
Nanda V, Wang T, Pjanic M, Liu B, Nguyen T, Matic LP, Hedin U, Koplev S, Ma L, Franzén O, Ruusalepp A, Schadt EE, Björkegren JLM, Montgomery SB, Snyder MP, Quertermous T, Leeper NJ, Miller CL. Nanda V, et al. Among authors: leeper nj. PLoS Genet. 2018 Nov 16;14(11):e1007755. doi: 10.1371/journal.pgen.1007755. eCollection 2018 Nov. PLoS Genet. 2018. PMID: 30444878 Free PMC article.
Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis.
Chun HJ, Ali ZA, Kojima Y, Kundu RK, Sheikh AY, Agrawal R, Zheng L, Leeper NJ, Pearl NE, Patterson AJ, Anderson JP, Tsao PS, Lenardo MJ, Ashley EA, Quertermous T. Chun HJ, et al. Among authors: leeper nj. J Clin Invest. 2008 Oct;118(10):3343-54. doi: 10.1172/JCI34871. J Clin Invest. 2008. PMID: 18769630 Free PMC article.
Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation.
Leeper NJ, Tedesco MM, Kojima Y, Schultz GM, Kundu RK, Ashley EA, Tsao PS, Dalman RL, Quertermous T. Leeper NJ, et al. Am J Physiol Heart Circ Physiol. 2009 May;296(5):H1329-35. doi: 10.1152/ajpheart.01341.2008. Epub 2009 Mar 20. Am J Physiol Heart Circ Physiol. 2009. PMID: 19304942 Free PMC article.
Endogenous regulation of cardiovascular function by apelin-APJ.
Charo DN, Ho M, Fajardo G, Kawana M, Kundu RK, Sheikh AY, Finsterbach TP, Leeper NJ, Ernst KV, Chen MM, Ho YD, Chun HJ, Bernstein D, Ashley EA, Quertermous T. Charo DN, et al. Among authors: leeper nj. Am J Physiol Heart Circ Physiol. 2009 Nov;297(5):H1904-13. doi: 10.1152/ajpheart.00686.2009. Epub 2009 Sep 18. Am J Physiol Heart Circ Physiol. 2009. PMID: 19767528 Free PMC article.
Loss of CDKN2B promotes p53-dependent smooth muscle cell apoptosis and aneurysm formation.
Leeper NJ, Raiesdana A, Kojima Y, Kundu RK, Cheng H, Maegdefessel L, Toh R, Ahn GO, Ali ZA, Anderson DR, Miller CL, Roberts SC, Spin JM, de Almeida PE, Wu JC, Xu B, Cheng K, Quertermous M, Kundu S, Kortekaas KE, Berzin E, Downing KP, Dalman RL, Tsao PS, Schadt EE, Owens GK, Quertermous T. Leeper NJ, et al. Arterioscler Thromb Vasc Biol. 2013 Jan;33(1):e1-e10. doi: 10.1161/ATVBAHA.112.300399. Epub 2012 Nov 15. Arterioscler Thromb Vasc Biol. 2013. PMID: 23162013 Free PMC article.
Disease-related growth factor and embryonic signaling pathways modulate an enhancer of TCF21 expression at the 6q23.2 coronary heart disease locus.
Miller CL, Anderson DR, Kundu RK, Raiesdana A, Nürnberg ST, Diaz R, Cheng K, Leeper NJ, Chen CH, Chang IS, Schadt EE, Hsiung CA, Assimes TL, Quertermous T. Miller CL, et al. Among authors: leeper nj. PLoS Genet. 2013;9(7):e1003652. doi: 10.1371/journal.pgen.1003652. Epub 2013 Jul 18. PLoS Genet. 2013. PMID: 23874238 Free PMC article.
Cyclin-dependent kinase inhibitor 2B regulates efferocytosis and atherosclerosis.
Kojima Y, Downing K, Kundu R, Miller C, Dewey F, Lancero H, Raaz U, Perisic L, Hedin U, Schadt E, Maegdefessel L, Quertermous T, Leeper NJ. Kojima Y, et al. Among authors: leeper nj. J Clin Invest. 2014 Mar;124(3):1083-97. doi: 10.1172/JCI70391. Epub 2014 Feb 17. J Clin Invest. 2014. PMID: 24531546 Free PMC article.
144 results