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smartPearls - Novel physically stable amorphous delivery system for poorly soluble dermal actives.
Int J Pharm. 2019 Jan 30;555:314-321. doi: 10.1016/j.ijpharm.2018.11.018. Epub 2018 Nov 13.
Int J Pharm. 2019.
PMID: 30439490
Review.
Dermal miconazole nitrate nanocrystals - formulation development, increased antifungal efficacy & skin penetration.
Pyo SM, Hespeler D, Keck CM, Müller RH.
Pyo SM, et al. Among authors: hespeler d.
Int J Pharm. 2017 Oct 5;531(1):350-359. doi: 10.1016/j.ijpharm.2017.08.108. Epub 2017 Sep 1.
Int J Pharm. 2017.
PMID: 28855137
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Glabridin smartPearls - Silica selection, production, amorphous stability and enhanced solubility.
Hespeler D, Kaltenbach J, Pyo SM.
Hespeler D, et al.
Int J Pharm. 2019 Apr 20;561:228-235. doi: 10.1016/j.ijpharm.2019.02.028. Epub 2019 Mar 2.
Int J Pharm. 2019.
PMID: 30836152
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smartPearls® for dermal bioavailability enhancement - Long-term stabilization of suspensions by viscoelasticity.
Hespeler D, Knoth D, Keck CM, Müller RH, Pyo SM.
Hespeler D, et al.
Int J Pharm. 2019 May 1;562:293-302. doi: 10.1016/j.ijpharm.2019.03.016. Epub 2019 Mar 8.
Int J Pharm. 2019.
PMID: 30853483
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Dermal smartPearls - Optimized silica particles for commercial products & mechanistic considerations.
Hespeler D, Pyo SM, Müller RH.
Hespeler D, et al.
Int J Pharm. 2020 Jan 25;574:118757. doi: 10.1016/j.ijpharm.2019.118757. Epub 2019 Nov 9.
Int J Pharm. 2020.
PMID: 31715366
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Nanoporous smartPearls for dermal application - Identification of optimal silica types and a scalable production process as prerequisites for marketed products.
Hespeler D, El Nomeiri S, Kaltenbach J, Müller RH.
Hespeler D, et al.
Beilstein J Nanotechnol. 2019 Aug 8;10:1666-1678. doi: 10.3762/bjnano.10.162. eCollection 2019.
Beilstein J Nanotechnol. 2019.
PMID: 31467828
Free PMC article.
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