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In Vivo Delivery of Synthetic Human DNA-Encoded Monoclonal Antibodies Protect against Ebolavirus Infection in a Mouse Model.
Patel A, Park DH, Davis CW, Smith TRF, Leung A, Tierney K, Bryan A, Davidson E, Yu X, Racine T, Reed C, Gorman ME, Wise MC, Elliott STC, Esquivel R, Yan J, Chen J, Muthumani K, Doranz BJ, Saphire EO, Crowe JE, Broderick KE, Kobinger GP, He S, Qiu X, Kobasa D, Humeau L, Sardesai NY, Ahmed R, Weiner DB. Patel A, et al. Among authors: chen j. Cell Rep. 2018 Nov 13;25(7):1982-1993.e4. doi: 10.1016/j.celrep.2018.10.062. Cell Rep. 2018. PMID: 30428362 Free PMC article.
In Vivo Delivery of a DNA-Encoded Monoclonal Antibody Protects Non-human Primates against Zika Virus.
Esquivel RN, Patel A, Kudchodkar SB, Park DH, Stettler K, Beltramello M, Allen JW, Mendoza J, Ramos S, Choi H, Borole P, Asija K, Bah M, Shaheen S, Chen J, Yan J, Durham AC, Smith TRF, Broderick K, Guibinga G, Muthumani K, Corti D, Humeau L, Weiner DB. Esquivel RN, et al. Among authors: chen j. Mol Ther. 2019 May 8;27(5):974-985. doi: 10.1016/j.ymthe.2019.03.005. Epub 2019 Apr 5. Mol Ther. 2019. PMID: 30962164 Free PMC article.
Active immunoprophylaxis with a synthetic DNA-encoded monoclonal anti-respiratory syncytial virus scFv-Fc fusion protein confers protection against infection and durable activity.
Schultheis K, Pugh HM, Oh J, Nguyen J, Yung B, Reed C, Cooch N, Chen J, Yan J, Muthumani K, Humeau LM, Weiner DB, Broderick KE, Smith TRF. Schultheis K, et al. Among authors: chen j. Hum Vaccin Immunother. 2020 Sep 1;16(9):2165-2175. doi: 10.1080/21645515.2020.1748979. Epub 2020 Jun 16. Hum Vaccin Immunother. 2020. PMID: 32544376 Free PMC article.
Protection against Borreliella burgdorferi infection mediated by a synthetically engineered DNA vaccine.
Guibinga GH, Sahay B, Brown H, Cooch N, Chen J, Yan J, Reed C, Mishra M, Yung B, Pugh H, Schultheis K, Esquivel RN, Weiner DB, Humeau LH, Broderick KE, Smith TRF. Guibinga GH, et al. Among authors: chen j. Hum Vaccin Immunother. 2020 Sep 1;16(9):2114-2122. doi: 10.1080/21645515.2020.1789408. Epub 2020 Aug 12. Hum Vaccin Immunother. 2020. PMID: 32783701 Free PMC article.
Molecular characterization of SARS-CoV-2 nucleocapsid protein.
Huang Y, Chen J, Chen S, Huang C, Li B, Li J, Jin Z, Zhang Q, Pan P, Du W, Liu L, Liu Z. Huang Y, et al. Among authors: chen j. Front Cell Infect Microbiol. 2024 May 23;14:1415885. doi: 10.3389/fcimb.2024.1415885. eCollection 2024. Front Cell Infect Microbiol. 2024. PMID: 38846351 Free PMC article. Review.
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