Nonnative aggregation of an IgG1 antibody in acidic conditions, part 2: nucleation and growth kinetics with competing growth mechanisms.
Brummitt RK, Nesta DP, Chang L, Kroetsch AM, Roberts CJ.
Brummitt RK, et al. Among authors: roberts cj.
J Pharm Sci. 2011 Jun;100(6):2104-19. doi: 10.1002/jps.22447. Epub 2011 Jan 6.
J Pharm Sci. 2011.
PMID: 21213307
Aggregation mechanisms as a function of pH were assessed for the IgG1 antibody described in Part 1 (Brummitt RK, Nesta DP, Chang L, Chase SF, Laue TM, Roberts CJ. Non-native aggregation of an IGG1 antibody in acidic conditions: 1. ...
Aggregation mechanisms as a function of pH were assessed for the IgG1 antibody described in Part 1 (Brummitt RK, Nesta DP, Chang L, Chase SF …