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Inhibiting APOBEC3 Activity with Single-Stranded DNA Containing 2'-Deoxyzebularine Analogues.
Biochemistry. 2019 Feb 5;58(5):391-400. doi: 10.1021/acs.biochem.8b00858. Epub 2018 Nov 28.
Biochemistry. 2019.
PMID: 30418757
Free PMC article.
Selective inhibition of APOBEC3 enzymes by single-stranded DNAs containing 2'-deoxyzebularine.
Barzak FM, Harjes S, Kvach MV, Kurup HM, Jameson GB, Filichev VV, Harjes E.
Barzak FM, et al.
Org Biomol Chem. 2019 Nov 6;17(43):9435-9441. doi: 10.1039/c9ob01781j.
Org Biomol Chem. 2019.
PMID: 31603457
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Differential Inhibition of APOBEC3 DNA-Mutator Isozymes by Fluoro- and Non-Fluoro-Substituted 2'-Deoxyzebularine Embedded in Single-Stranded DNA.
Kvach MV, Barzak FM, Harjes S, Schares HAM, Kurup HM, Jones KF, Sutton L, Donahue J, D'Aquila RT, Jameson GB, Harki DA, Krause KL, Harjes E, Filichev VV.
Kvach MV, et al. Among authors: barzak fm.
Chembiochem. 2020 Apr 1;21(7):1028-1035. doi: 10.1002/cbic.201900505. Epub 2019 Dec 19.
Chembiochem. 2020.
PMID: 31633265
Free PMC article.
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Small-Angle X-ray Scattering Models of APOBEC3B Catalytic Domain in a Complex with a Single-Stranded DNA Inhibitor.
Barzak FM, Ryan TM, Kvach MV, Kurup HM, Aihara H, Harris RS, Filichev VV, Harjes E, Jameson GB.
Barzak FM, et al.
Viruses. 2021 Feb 12;13(2):290. doi: 10.3390/v13020290.
Viruses. 2021.
PMID: 33673243
Free PMC article.
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Small-Angle X-ray Scattering (SAXS) Measurements of APOBEC3G Provide Structural Basis for Binding of Single-Stranded DNA and Processivity.
Barzak FM, Ryan TM, Mohammadzadeh N, Harjes S, Kvach MV, Kurup HM, Krause KL, Chelico L, Filichev VV, Harjes E, Jameson GB.
Barzak FM, et al.
Viruses. 2022 Sep 6;14(9):1974. doi: 10.3390/v14091974.
Viruses. 2022.
PMID: 36146779
Free PMC article.
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A novel RNF125 variant associated with Tenorio syndrome alters ubiquitin chain binding.
Barzak FM, Lu A, Geltzeiler AR, Ledgerwood EC, Chung WK, Day CL.
Barzak FM, et al.
Clin Genet. 2024 Mar;105(3):254-261. doi: 10.1111/cge.14457. Epub 2023 Nov 20.
Clin Genet. 2024.
PMID: 37986019
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Zinc finger 1 of the RING E3 ligase, RNF125, interacts with the E2 to enhance ubiquitylation.
Middleton AJ, Barzak FM, Fokkens TJ, Nguyen K, Day CL.
Middleton AJ, et al. Among authors: barzak fm.
Structure. 2023 Oct 5;31(10):1208-1219.e5. doi: 10.1016/j.str.2023.07.007. Epub 2023 Aug 3.
Structure. 2023.
PMID: 37541247
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Design, Synthesis, and Evaluation of a Cross-Linked Oligonucleotide as the First Nanomolar Inhibitor of APOBEC3A.
Kurup HM, Kvach MV, Harjes S, Barzak FM, Jameson GB, Harjes E, Filichev VV.
Kurup HM, et al. Among authors: barzak fm.
Biochemistry. 2022 Nov 15;61(22):2568-2578. doi: 10.1021/acs.biochem.2c00449. Epub 2022 Oct 27.
Biochemistry. 2022.
PMID: 36302365
Free PMC article.
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