Salek-Ardakani S - Search Results

1

Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab.

Chin SM, Kimberlin CR, Roe-Zurz Z, Zhang P, Xu A, Liao-Chan S, Sen D, Nager AR, Oakdale NS, Brown C, Wang F, Yang Y, Lindquist K, Yeung YA, Salek-Ardakani S, Chaparro-Riggers J. Chin SM, et al. Nat Commun. 2018 Nov 8;9(1):4679. doi: 10.1038/s41467-018-07136-7. Nat Commun. 2018. PMID: 30410017 Free PMC article.

2

Ligand-Blocking and Membrane-Proximal Domain Targeting Anti-OX40 Antibodies Mediate Potent T Cell-Stimulatory and Anti-Tumor Activity.

Zhang P, Tu GH, Wei J, Santiago P, Larrabee LR, Liao-Chan S, Mistry T, Chu ML, Sai T, Lindquist K, Long H, Chaparro-Riggers J, Salek-Ardakani S, Yeung YA. Zhang P, et al. Cell Rep. 2019 Jun 11;27(11):3117-3123.e5. doi: 10.1016/j.celrep.2019.05.027. Cell Rep. 2019. PMID: 31189099 Free article.

3

CD40 agonist-induced IL-12p40 potentiates hepatotoxicity.

Bonnans C, Thomas G, He W, Jung B, Chen W, Liao M, Heyen J, Buetow B, Pillai S, Matsumoto D, Chaparro-Riggers J, Salek-Ardakani S, Qu Y. Bonnans C, et al. J Immunother Cancer. 2020 May;8(1):e000624. doi: 10.1136/jitc-2020-000624. J Immunother Cancer. 2020. PMID: 32474414 Free PMC article.

4

Pharmacologic Properties and Preclinical Activity of Sasanlimab, A High-affinity Engineered Anti-Human PD-1 Antibody.

Al-Khami AA, Youssef S, Abdiche Y, Nguyen H, Chou J, Kimberlin CR, Chin SM, Kamperschroer C, Jessen B, Kern B, Budimir N, Dillon CP, Xu A, Clark JD, Chou J, Kraynov E, Rajpal A, Lin JC, Salek-Ardakani S. Al-Khami AA, et al. Mol Cancer Ther. 2020 Oct;19(10):2105-2116. doi: 10.1158/1535-7163.MCT-20-0093. Epub 2020 Aug 26. Mol Cancer Ther. 2020. PMID: 32847983

5

FcγRIIB engagement drives agonistic activity of Fc-engineered αOX40 antibody to stimulate human tumor-infiltrating T cells.

Campos Carrascosa L, van Beek AA, de Ruiter V, Doukas M, Wei J, Fisher TS, Ching K, Yang W, van Loon K, Boor PPC, Rakké YS, Noordam L, Doornebosch P, Grünhagen D, Verhoef K, Polak WG, IJzermans JNM, Ni I, Yeung YA, Salek-Ardakani S, Sprengers D, Kwekkeboom J. Campos Carrascosa L, et al. J Immunother Cancer. 2020 Sep;8(2):e000816. doi: 10.1136/jitc-2020-000816. J Immunother Cancer. 2020. PMID: 32900860 Free PMC article.

6

Dual checkpoint blockade of CD47 and PD-L1 using an affinity-tuned bispecific antibody maximizes antitumor immunity.

Chen SH, Dominik PK, Stanfield J, Ding S, Yang W, Kurd N, Llewellyn R, Heyen J, Wang C, Melton Z, Van Blarcom T, Lindquist KC, Chaparro-Riggers J, Salek-Ardakani S. Chen SH, et al. Among authors: salek ardakani s. J Immunother Cancer. 2021 Oct;9(10):e003464. doi: 10.1136/jitc-2021-003464. J Immunother Cancer. 2021. PMID: 34599020 Free PMC article.

7

EZH2 Inhibition Compromises α4-1BB-Mediated Antitumor Efficacy by Reducing the Survival and Effector Programming of CD8⁺ T Cells.

Stairiker CJ, Pfister SX, Hendrickson E, Yang W, Xie T, Lee C, Zhang H, Dillon C, Thomas GD, Salek-Ardakani S. Stairiker CJ, et al. Among authors: salek ardakani s. Front Immunol. 2021 Nov 24;12:770080. doi: 10.3389/fimmu.2021.770080. eCollection 2021. Front Immunol. 2021. PMID: 34925340 Free PMC article.

8

The costimulation-regulated duration of PKB activation controls T cell longevity.

Song J, Salek-Ardakani S, Rogers PR, Cheng M, Van Parijs L, Croft M. Song J, et al. Nat Immunol. 2004 Feb;5(2):150-8. doi: 10.1038/ni1030. Epub 2004 Jan 18. Nat Immunol. 2004. PMID: 14730361

9

Hypercostimulation through 4-1BB distorts homeostasis of immune cells.

Lee SW, Salek-Ardakani S, Mittler RS, Croft M. Lee SW, et al. J Immunol. 2009 Jun 1;182(11):6753-62. doi: 10.4049/jimmunol.0803241. J Immunol. 2009. PMID: 19454670 Free PMC article.

10

Inhibition of glucose metabolism selectively targets autoreactive follicular helper T cells.

Choi SC, Titov AA, Abboud G, Seay HR, Brusko TM, Roopenian DC, Salek-Ardakani S, Morel L. Choi SC, et al. Nat Commun. 2018 Oct 22;9(1):4369. doi: 10.1038/s41467-018-06686-0. Nat Commun. 2018. PMID: 30348969 Free PMC article.

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