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Tolerance to apoptotic cells is regulated by indoleamine 2,3-dioxygenase.
Ravishankar B, Liu H, Shinde R, Chandler P, Baban B, Tanaka M, Munn DH, Mellor AL, Karlsson MC, McGaha TL. Ravishankar B, et al. Among authors: mcgaha tl. Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3909-14. doi: 10.1073/pnas.1117736109. Epub 2012 Feb 21. Proc Natl Acad Sci U S A. 2012. PMID: 22355111 Free PMC article.
Amino acid metabolism inhibits antibody-driven kidney injury by inducing autophagy.
Chaudhary K, Shinde R, Liu H, Gnana-Prakasam JP, Veeranan-Karmegam R, Huang L, Ravishankar B, Bradley J, Kvirkvelia N, McMenamin M, Xiao W, Kleven D, Mellor AL, Madaio MP, McGaha TL. Chaudhary K, et al. Among authors: mcgaha tl. J Immunol. 2015 Jun 15;194(12):5713-24. doi: 10.4049/jimmunol.1500277. Epub 2015 May 15. J Immunol. 2015. PMID: 25980011 Free PMC article.
The PTEN pathway in Tregs is a critical driver of the suppressive tumor microenvironment.
Sharma MD, Shinde R, McGaha TL, Huang L, Holmgaard RB, Wolchok JD, Mautino MR, Celis E, Sharpe AH, Francisco LM, Powell JD, Yagita H, Mellor AL, Blazar BR, Munn DH. Sharma MD, et al. Among authors: mcgaha tl. Sci Adv. 2015 Nov 6;1(10):e1500845. doi: 10.1126/sciadv.1500845. eCollection 2015 Nov. Sci Adv. 2015. PMID: 26601142 Free PMC article.
Type I Interferon in Chronic Virus Infection and Cancer.
Snell LM, McGaha TL, Brooks DG. Snell LM, et al. Among authors: mcgaha tl. Trends Immunol. 2017 Aug;38(8):542-557. doi: 10.1016/j.it.2017.05.005. Epub 2017 May 31. Trends Immunol. 2017. PMID: 28579323 Free PMC article. Review.
Apoptotic cell-induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans.
Shinde R, Hezaveh K, Halaby MJ, Kloetgen A, Chakravarthy A, da Silva Medina T, Deol R, Manion KP, Baglaenko Y, Eldh M, Lamorte S, Wallace D, Chodisetti SB, Ravishankar B, Liu H, Chaudhary K, Munn DH, Tsirigos A, Madaio M, Gabrielsson S, Touma Z, Wither J, De Carvalho DD, McGaha TL. Shinde R, et al. Among authors: mcgaha tl. Nat Immunol. 2018 Jun;19(6):571-582. doi: 10.1038/s41590-018-0107-1. Epub 2018 May 14. Nat Immunol. 2018. PMID: 29760532 Free PMC article.
74 results