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Plasma Tie2 is a tumor vascular response biomarker for VEGF inhibitors in metastatic colorectal cancer.
Jayson GC, Zhou C, Backen A, Horsley L, Marti-Marti K, Shaw D, Mescallado N, Clamp A, Saunders MP, Valle JW, Mullamitha S, Braun M, Hasan J, McEntee D, Simpson K, Little RA, Watson Y, Cheung S, Roberts C, Ashcroft L, Manoharan P, Scherer SJ, Del Puerto O, Jackson A, O'Connor JPB, Parker GJM, Dive C. Jayson GC, et al. Among authors: saunders mp. Nat Commun. 2018 Nov 7;9(1):4672. doi: 10.1038/s41467-018-07174-1. Nat Commun. 2018. PMID: 30405103 Free PMC article. Clinical Trial.
Blockade of platelet-derived growth factor receptor-beta by CDP860, a humanized, PEGylated di-Fab', leads to fluid accumulation and is associated with increased tumor vascularized volume.
Jayson GC, Parker GJ, Mullamitha S, Valle JW, Saunders M, Broughton L, Lawrance J, Carrington B, Roberts C, Issa B, Buckley DL, Cheung S, Davies K, Watson Y, Zinkewich-Péotti K, Rolfe L, Jackson A. Jayson GC, et al. J Clin Oncol. 2005 Feb 10;23(5):973-81. doi: 10.1200/JCO.2005.01.032. Epub 2004 Oct 4. J Clin Oncol. 2005. PMID: 15466784 Clinical Trial.
Impact of laparotomy and liver resection on the peritoneal concentrations of fibroblast growth factor 2, vascular endothelial growth factor and hepatocyte growth factor.
Whitworth MK, Sheen A, Rosa DD, Duff SE, Ryder D, Burumdayal A, Wiener K, Hawkins RE, Saunders M, Valle JW, Sherlock D, Jayson GC. Whitworth MK, et al. J Cancer Res Clin Oncol. 2006 Jan;132(1):41-4. doi: 10.1007/s00432-005-0037-9. Epub 2005 Oct 26. J Cancer Res Clin Oncol. 2006. PMID: 16249905
Vaccination of colorectal cancer patients with modified vaccinia Ankara delivering the tumor antigen 5T4 (TroVax) induces immune responses which correlate with disease control: a phase I/II trial.
Harrop R, Connolly N, Redchenko I, Valle J, Saunders M, Ryan MG, Myers KA, Drury N, Kingsman SM, Hawkins RE, Carroll MW. Harrop R, et al. Clin Cancer Res. 2006 Jun 1;12(11 Pt 1):3416-24. doi: 10.1158/1078-0432.CCR-05-2732. Clin Cancer Res. 2006. PMID: 16740766 Clinical Trial.
159 results