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Mechanical strain determines the site-specific localization of inflammation and tissue damage in arthritis.
Cambré I, Gaublomme D, Burssens A, Jacques P, Schryvers N, De Muynck A, Meuris L, Lambrecht S, Carter S, de Bleser P, Saeys Y, Van Hoorebeke L, Kollias G, Mack M, Simoens P, Lories R, Callewaert N, Schett G, Elewaut D. Cambré I, et al. Among authors: schett g. Nat Commun. 2018 Nov 5;9(1):4613. doi: 10.1038/s41467-018-06933-4. Nat Commun. 2018. PMID: 30397205 Free PMC article.
Osteoclasts are essential for TNF-alpha-mediated joint destruction.
Redlich K, Hayer S, Ricci R, David JP, Tohidast-Akrad M, Kollias G, Steiner G, Smolen JS, Wagner EF, Schett G. Redlich K, et al. Among authors: schett g. J Clin Invest. 2002 Nov;110(10):1419-27. doi: 10.1172/JCI15582. J Clin Invest. 2002. PMID: 12438440 Free PMC article.
Repair of local bone erosions and reversal of systemic bone loss upon therapy with anti-tumor necrosis factor in combination with osteoprotegerin or parathyroid hormone in tumor necrosis factor-mediated arthritis.
Redlich K, Görtz B, Hayer S, Zwerina J, Doerr N, Kostenuik P, Bergmeister H, Kollias G, Steiner G, Smolen JS, Schett G. Redlich K, et al. Among authors: schett g. Am J Pathol. 2004 Feb;164(2):543-55. doi: 10.1016/S0002-9440(10)63144-6. Am J Pathol. 2004. PMID: 14742260 Free PMC article.
Autoimmunity and rheumatoid arthritis.
Smolen JS, Hayer S, Schett G, Redlich K, Aringer M, Kollias G, Wagner E, Steiner G. Smolen JS, et al. Among authors: schett g. Autoimmun Rev. 2004 Jun;3 Suppl 1:S23. Autoimmun Rev. 2004. PMID: 15309784 Review. No abstract available.
Aberrant expression of the autoantigen heterogeneous nuclear ribonucleoprotein-A2 (RA33) and spontaneous formation of rheumatoid arthritis-associated anti-RA33 autoantibodies in TNF-alpha transgenic mice.
Hayer S, Tohidast-Akrad M, Haralambous S, Jahn-Schmid B, Skriner K, Trembleau S, Dumortier H, Pinol-Roma S, Redlich K, Schett G, Muller S, Kollias G, Smolen J, Steiner G. Hayer S, et al. Among authors: schett g. J Immunol. 2005 Dec 15;175(12):8327-36. doi: 10.4049/jimmunol.175.12.8327. J Immunol. 2005. PMID: 16339574
12/15-lipoxygenase counteracts inflammation and tissue damage in arthritis.
Krönke G, Katzenbeisser J, Uderhardt S, Zaiss MM, Scholtysek C, Schabbauer G, Zarbock A, Koenders MI, Axmann R, Zwerina J, Baenckler HW, van den Berg W, Voll RE, Kühn H, Joosten LA, Schett G. Krönke G, et al. Among authors: schett g. J Immunol. 2009 Sep 1;183(5):3383-9. doi: 10.4049/jimmunol.0900327. Epub 2009 Aug 12. J Immunol. 2009. PMID: 19675173 Free article.
The alpha-isoform of p38 MAPK specifically regulates arthritic bone loss.
Böhm C, Hayer S, Kilian A, Zaiss MM, Finger S, Hess A, Engelke K, Kollias G, Krönke G, Zwerina J, Schett G, David JP. Böhm C, et al. Among authors: schett g. J Immunol. 2009 Nov 1;183(9):5938-47. doi: 10.4049/jimmunol.0901026. Epub 2009 Oct 14. J Immunol. 2009. PMID: 19828631
1,031 results