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Cell Surface Notch Ligand DLL3 is a Therapeutic Target in Isocitrate Dehydrogenase-mutant Glioma.
Spino M, Kurz SC, Chiriboga L, Serrano J, Zeck B, Sen N, Patel S, Shen G, Vasudevaraja V, Tsirigos A, Suryadevara CM, Frenster JD, Tateishi K, Wakimoto H, Jain R, Riina HA, Nicolaides TP, Sulman EP, Cahill DP, Golfinos JG, Isse K, Saunders LR, Zagzag D, Placantonakis DG, Snuderl M, Chi AS. Spino M, et al. Among authors: frenster jd. Clin Cancer Res. 2019 Feb 15;25(4):1261-1271. doi: 10.1158/1078-0432.CCR-18-2312. Epub 2018 Nov 5. Clin Cancer Res. 2019. PMID: 30397180 Free PMC article.
GPR133 (ADGRD1), an adhesion G-protein-coupled receptor, is necessary for glioblastoma growth.
Bayin NS, Frenster JD, Kane JR, Rubenstein J, Modrek AS, Baitalmal R, Dolgalev I, Rudzenski K, Scarabottolo L, Crespi D, Redaelli L, Snuderl M, Golfinos JG, Doyle W, Pacione D, Parker EC, Chi AS, Heguy A, MacNeil DJ, Shohdy N, Zagzag D, Placantonakis DG. Bayin NS, et al. Among authors: frenster jd. Oncogenesis. 2016 Oct 24;5(10):e263. doi: 10.1038/oncsis.2016.63. Oncogenesis. 2016. PMID: 27775701 Free PMC article.
GPR133 Promotes Glioblastoma Growth in Hypoxia.
Frenster JD, Inocencio JF, Xu Z, Dhaliwal J, Alghamdi A, Zagzag D, Bayin NS, Placantonakis DG. Frenster JD, et al. Neurosurgery. 2017 Sep 1;64(CN_suppl_1):177-181. doi: 10.1093/neuros/nyx227. Neurosurgery. 2017. PMID: 28899043 Free PMC article. No abstract available.
Notch signaling regulates metabolic heterogeneity in glioblastoma stem cells.
Bayin NS, Frenster JD, Sen R, Si S, Modrek AS, Galifianakis N, Dolgalev I, Ortenzi V, Illa-Bochaca I, Khahera A, Serrano J, Chiriboga L, Zagzag D, Golfinos JG, Doyle W, Tsirigos A, Heguy A, Chesler M, Barcellos-Hoff MH, Snuderl M, Placantonakis DG. Bayin NS, et al. Among authors: frenster jd. Oncotarget. 2017 May 23;8(39):64932-64953. doi: 10.18632/oncotarget.18117. eCollection 2017 Sep 12. Oncotarget. 2017. PMID: 29029402 Free PMC article.
Low-Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2.
Modrek AS, Golub D, Khan T, Bready D, Prado J, Bowman C, Deng J, Zhang G, Rocha PP, Raviram R, Lazaris C, Stafford JM, LeRoy G, Kader M, Dhaliwal J, Bayin NS, Frenster JD, Serrano J, Chiriboga L, Baitalmal R, Nanjangud G, Chi AS, Golfinos JG, Wang J, Karajannis MA, Bonneau RA, Reinberg D, Tsirigos A, Zagzag D, Snuderl M, Skok JA, Neubert TA, Placantonakis DG. Modrek AS, et al. Among authors: frenster jd. Cell Rep. 2017 Oct 31;21(5):1267-1280. doi: 10.1016/j.celrep.2017.10.009. Cell Rep. 2017. PMID: 29091765 Free PMC article.
Isolation of Glioblastoma Stem Cells with Flow Cytometry.
Inocencio J, Frenster JD, Placantonakis DG. Inocencio J, et al. Among authors: frenster jd. Methods Mol Biol. 2018;1741:71-79. doi: 10.1007/978-1-4939-7659-1_5. Methods Mol Biol. 2018. PMID: 29392691
20 results