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Optimized pipeline of MuTect and GATK tools to improve the detection of somatic single nucleotide polymorphisms in whole-exome sequencing data.
do Valle ÍF, Giampieri E, Simonetti G, Padella A, Manfrini M, Ferrari A, Papayannidis C, Zironi I, Garonzi M, Bernardi S, Delledonne M, Martinelli G, Remondini D, Castellani G. do Valle ÍF, et al. Among authors: simonetti g. BMC Bioinformatics. 2016 Nov 8;17(Suppl 12):341. doi: 10.1186/s12859-016-1190-7. BMC Bioinformatics. 2016. PMID: 28185561 Free PMC article.
The E3 ubiquitin ligase WWP1 sustains the growth of acute myeloid leukaemia.
Sanarico AG, Ronchini C, Croce A, Memmi EM, Cammarata UA, De Antoni A, Lavorgna S, Divona M, Giacò L, Melloni GEM, Brendolan A, Simonetti G, Martinelli G, Mancuso P, Bertolini F, Coco FL, Melino G, Pelicci PG, Bernassola F. Sanarico AG, et al. Among authors: simonetti g. Leukemia. 2018 Apr;32(4):911-919. doi: 10.1038/leu.2017.342. Epub 2017 Dec 6. Leukemia. 2018. PMID: 29209041 Free PMC article.
Aneuploidy: Cancer strength or vulnerability?
Simonetti G, Bruno S, Padella A, Tenti E, Martinelli G. Simonetti G, et al. Int J Cancer. 2019 Jan 1;144(1):8-25. doi: 10.1002/ijc.31718. Epub 2018 Oct 31. Int J Cancer. 2019. PMID: 29981145 Free PMC article. Review.
Main changes in European Clinical Trials Regulation (No 536/2014).
Tenti E, Simonetti G, Bochicchio MT, Martinelli G. Tenti E, et al. Among authors: simonetti g. Contemp Clin Trials Commun. 2018 May 17;11:99-101. doi: 10.1016/j.conctc.2018.05.014. eCollection 2018 Sep. Contemp Clin Trials Commun. 2018. PMID: 30003173 Free PMC article.
Aneuploid acute myeloid leukemia exhibits a signature of genomic alterations in the cell cycle and protein degradation machinery.
Simonetti G, Padella A, do Valle IF, Fontana MC, Fonzi E, Bruno S, Baldazzi C, Guadagnuolo V, Manfrini M, Ferrari A, Paolini S, Papayannidis C, Marconi G, Franchini E, Zuffa E, Laginestra MA, Zanotti F, Astolfi A, Iacobucci I, Bernardi S, Sazzini M, Ficarra E, Hernandez JM, Vandenberghe P, Cools J, Bullinger L, Ottaviani E, Testoni N, Cavo M, Haferlach T, Castellani G, Remondini D, Martinelli G. Simonetti G, et al. Cancer. 2019 Mar 1;125(5):712-725. doi: 10.1002/cncr.31837. Epub 2018 Nov 27. Cancer. 2019. PMID: 30480765 Free PMC article.
Chronic myeloid leukemia stem cells.
Houshmand M, Simonetti G, Circosta P, Gaidano V, Cignetti A, Martinelli G, Saglio G, Gale RP. Houshmand M, et al. Among authors: simonetti g. Leukemia. 2019 Jul;33(7):1543-1556. doi: 10.1038/s41375-019-0490-0. Epub 2019 May 24. Leukemia. 2019. PMID: 31127148 Free PMC article. Review.
The acetyltransferase GCN5 maintains ATRA-resistance in non-APL AML.
Kahl M, Brioli A, Bens M, Perner F, Kresinsky A, Schnetzke U, Hinze A, Sbirkov Y, Stengel S, Simonetti G, Martinelli G, Petrie K, Zelent A, Böhmer FD, Groth M, Ernst T, Heidel FH, Scholl S, Hochhaus A, Schenk T. Kahl M, et al. Among authors: simonetti g. Leukemia. 2019 Nov;33(11):2628-2639. doi: 10.1038/s41375-019-0581-y. Epub 2019 Oct 1. Leukemia. 2019. PMID: 31576004
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